Ratiometric electrochemical detection of tryptophan based on ferrocene and carboxylated-pillar[6]arene hybrid metal–organic layers

Abstract

Metal-organic layers (MOLs), which have an ultrathin structure, are a novel class of two dimensional coordination polymers. In comparison with three dimensional metal-organic frameworks, MOLs have more accessible active sites...

Carboxylated Pillar[5]arene Meets Medicinal Biguanides: Host–Guest Complexes with Alexidine and Phenformin in the Crystal and Solution/Gas Phase

“…First reported by Ogoshi in 2010, carboxylated pillar­[ n ]­arenes have received a lot of attention in aqueous supramolecular chemistry . For example, they have been used in various host–guest assemblies, , as sensors, drug delivery systems, , in supramolecular chemotherapy, , for cell imaging, , or as scaffolds for supramolecular polymers . However, their solid-state assemblies and structures have barely been touched in comparison to flourishing solution host–guest chemistry.…”

“…We decided to fill this gap by directing our attention to the crystallization and structure elucidation of carboxylated pillar[n]arenes and their supramolecular assemblies. We managed for the first time to trap in the crystal state both pillar [5]arene 14 and pillar [6]arene 15 in the form of host−guest complexes. We have shown that carboxylated pillar [5]arene (CPA5) forms inclusion and exclusion complexes with electron-deficient viologen guests 16 and coordination complexes with metal cations.…”

“…Figure 11. Crystal packing of the carboxylated pillar[6]arene− phenformin complex viewed along a direction. Included phenformin molecules are colored blue, and phenformin complexed outside the cavities is colored sea green and pink.…”