Rational design and additive manufacturing of alumina-based lattice structures for bone implant

Lei, Haoyang; Song, Changhui; Liu, Zibin; Deng, Zhengtai; Yuan, Fu‐Zhen; Yu, Jia‐Kuo; Yang, Yongqiang

doi:10.1016/j.matdes.2022.111003

Cited by 15 publications

(3 citation statements)

References 43 publications

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“…Indeed, Frontiers in Materials frontiersin.org permeability, pressure drop and fluid flow-induced wall shear stress are important properties to be considered for porous parts to be used in numerous fields, namely, biomedical, environmental, energy, space and aerospace. To this extent, computational fluid dynamics (CFD) is a useful tool to optimize the structure of the object to be printed, such as scaffolds (Ali et al, 2020;Lei et al, 2022;Prakoso et al, 2023), membranes/filters (Kovacev et al, 2021;Chevarin et al, 2023), nozzles (Naveen Kumar et al, 2017). In the case of bone tissue engineering, in which bioactivity, cell differentiation and proliferation within the scaffolds are fundamental, numerous parameters of the scaffold can be varied and tested thanks to CFD avoiding expensive and timeconsuming experimental trials.…”

Section: Elaboration Of the 3d Modelmentioning

confidence: 99%

“…In the case of bone tissue engineering, in which bioactivity, cell differentiation and proliferation within the scaffolds are fundamental, numerous parameters of the scaffold can be varied and tested thanks to CFD avoiding expensive and timeconsuming experimental trials. For example, considering the permeability of different human bones (vertebral body 0.359 × 10 −8 m 2 ; vertebral body lumbar 1.09 × 10 −8 m 2 ; tibia 0.768 × 10 −8 m 2 ), that is strictly related to the transportation of nutrition and oxygen for cells proliferation and growth, scaffolds can properly be modeled and validated trough CFD according to their final application (Lei et al, 2022). Also in the environmental field, for example, in the case of exhaust gas purification with ceramic substrates coated with catalytic converter, CFD can aid the design of the new catalytic supports.…”

Section: Elaboration Of the 3d Modelmentioning

confidence: 99%

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Vat-photopolymerization of ceramic materials: exploring current applications in advanced multidisciplinary fields

Fiume,

Coppola,

Montanaro

et al. 2023

Front. Mater.

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Additive manufacturing has brought about a real revolution in the manufacture of objects in a variety of application areas, overturning the traditional paradigm based on subtractive approaches. The potential benefits deriving from the application of these techniques in the field of ceramic materials extend to different industrial sectors, leading to shorter, more accurate and cost-effective manufacturing processes. Within the present review, we provide a transversal analysis of the state-of-the-art of the applications of vat-photopolymerization technologies, namely, stereolithography and digital light processing in relevant technological industrial/research fields of our times, including biomedicine, energy, environment, space and aerospace, with a special focus on current trends and project-specific requirements. Unmet challenges and future developments will be discussed as well, providing readers a transfer of knowledge and “lessons learned” from one field to the other, being this approach aimed at the further growth of the technology towards its industrialization and market uptake.

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Section: Elaboration Of the 3d Modelmentioning

confidence: 99%

Section: Elaboration Of the 3d Modelmentioning

confidence: 99%

Vat-photopolymerization of ceramic materials: exploring current applications in advanced multidisciplinary fields

Fiume,

Coppola,

Montanaro

et al. 2023

Front. Mater.

View full text Add to dashboard Cite

show abstract

“…A commonly used method for designing AM products is based on topology optimization of their lattice structure. The optimal choice of the lattice‐cell size and shape was recently discussed in References 18–24. Changes in the shape and size of pores in a lattice cause variation in mechanical properties.…”

Section: Introductionmentioning

confidence: 99%

Method of computational design for additive manufacturing of hip endoprosthesis based on basic‐cell concept

Bolshakov,

Kuchumov,

Kharin

et al. 2024

Numer Methods Biomed Eng

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Endoprosthetic hip replacement is the conventional way to treat osteoarthritis or a fracture of a dysfunctional joint. Different manufacturing methods are employed to create reliable patient‐specific devices with long‐term performance and biocompatibility. Recently, additive manufacturing has become a promising technique for the fabrication of medical devices, because it allows to produce complex samples with various structures of pores. Moreover, the limitations of traditional fabrication methods can be avoided. It is known that a well‐designed porous structure provides a better proliferation of cells, leading to improved bone remodeling. Additionally, porosity can be used to adjust the mechanical properties of designed structures. This makes the design and choice of the structure's basic cell a crucial task. This study focuses on a novel computational method, based on the basic‐cell concept to design a hip endoprosthesis with an unregularly complex structure. A cube with spheroid pores was utilized as a basic cell, with each cell having its own porosity and mechanical properties. A novelty of the suggested method is in its combination of the topology optimization method and the structural design algorithm. Bending and compression cases were analyzed for a cylinder structure and two hip implants. The ability of basic‐cell geometry to influence the structure's stress–strain state was shown. The relative change in the volume of the original structure and the designed cylinder structure was 6.8%. Computational assessments of a stress–strain state using the proposed method and direct modeling were carried out. The volumes of the two types of implants decreased by 9% and 11%, respectively. The maximum von Mises stress was 600 MPa in the initial design. After the algorithm application, it increased to 630 MPa for the first type of implant, while it is not changing in the second type of implant. At the same time, the load‐bearing capacity of the hip endoprostheses was retained. The internal structure of the optimized implants was significantly different from the traditional designs, but better structural integrity is likely to be achieved with less material. Additionally, this method leads to time reduction both for the initial design and its variations. Moreover, it enables to produce medical implants with specific functional structures with an additive manufacturing method avoiding the constraints of traditional technologies.

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Mechanical Properties of 3D-Printed Cellular Ceramic Structures

He,

Zhang

2024

Comprehensive Mechanics of Materials

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Rational design and additive manufacturing of alumina-based lattice structures for bone implant

Cited by 15 publications

References 43 publications

Vat-photopolymerization of ceramic materials: exploring current applications in advanced multidisciplinary fields

Vat-photopolymerization of ceramic materials: exploring current applications in advanced multidisciplinary fields

Method of computational design for additive manufacturing of hip endoprosthesis based on basic‐cell concept

Mechanical Properties of 3D-Printed Cellular Ceramic Structures

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