Rational design of a large Stokes shift xanthene–benzothiozolium dyad for probing cysteine in mitochondria

Cai, Songtao; Liu, Qiuchen; Liu, Chang; He, Song; Zhao, Liancheng; Zeng, Xianshun; Gong, Jicheng

doi:10.1039/d1tb02639a

Cited by 7 publications

(1 citation statement)

References 38 publications

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“…类似地, 王建红等 [51] 于同年报道了一例以 2-氯苯甲酸酯为识别基团的线粒体半胱氨酸荧光探针 14. 2022 年, 曾宪顺等 [52] [53] 基于吡啶鎓离子与丙烯酸酯识别基团构筑了半胱氨酸荧光探针 16. 该探针在水相中具有良好的双光子特性, 在 750 nm 激发下可以实现 150 μm 的组织穿透深度.…”

Section: 线粒体靶向型半胱氨酸荧光探针unclassified

Research Progress of Fluorescent Probes for Cysteine Targeting Cellular Organelles

Liu¹,

Jing²

2023

Chinese Journal of Organic Chemistry

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As an important endogenous biothiol, cysteine is involved in various physiological processes. Besides, cysteine also plays an important role in the regulation of intracellular redox levels and the synthesis of bioactive substances. Cellular organelles all act an essential role in the life process, but different cellular organelles have their own unique functions, which makes the mechanism of cysteine in different organelles may be different. The high sensitivity and in situ analyze ability of fluorescent probes provide a method to monitor cysteine in different organelles, which is helpful to understand the mechanism of cysteine in physiological process more comprehensively. In this review, the recent reports on cysteine specific fluorescent probes are classified according to their targeted organelles. Besides, the property of those probes, including their structure, response mechanism, spectral properties and biological applications, is summarized.

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Section: 线粒体靶向型半胱氨酸荧光探针unclassified

Research Progress of Fluorescent Probes for Cysteine Targeting Cellular Organelles

Liu¹,

Jing²

2023

Chinese Journal of Organic Chemistry

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Assessment of environmental and biological stress using mitochondria-targeted red-emitting and near-infrared fluorescent probes for biothiol analysis: a review

Lu,

Li,

2024

Environ Chem Lett

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Evaluation of erastin synergized cisplatin anti-nasopharyngeal carcinoma effect with a glutathione-activated near-infrared fluorescent probe

Tang

et al. 2024

Chinese Chemical Letters

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Rational design of a large Stokes shift xanthene–benzothiozolium dyad for probing cysteine in mitochondria

Abstract: Xanthene-modified cyanine dyes are considered to be an effective means to extend the emission wavelength and improve the photo-stability of cyanine dyes. However, the fluorophores obtained by this strategy generally...

Cited by 7 publications

References 38 publications

Research Progress of Fluorescent Probes for Cysteine Targeting Cellular Organelles

Research Progress of Fluorescent Probes for Cysteine Targeting Cellular Organelles

Assessment of environmental and biological stress using mitochondria-targeted red-emitting and near-infrared fluorescent probes for biothiol analysis: a review

Evaluation of erastin synergized cisplatin anti-nasopharyngeal carcinoma effect with a glutathione-activated near-infrared fluorescent probe

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