Rational Design of ICT-Based Fluorescent Probe with AIE and NIR Properties for Hypochlorite Determination

Abstract

In recent years, the easily synthesized fluorescent probes with good photophysical and sensing properties have attracted widespread attention. Herein, by utilizing the fluorescence regulation effect of electron push-pull effect and the oxidation property of hypochlorite (ClO-) to C=N double bonds, we proposed two intramolecular charge transfer (ICT)-based fluorescent probes with typical aggregation-induced emission (AIE) properties for ClO- detection. The synthesis process of the two probes is very convenient, and both of them can exhibit significant colorimetric and fluorescence changes within 3 min in the presence of ClO-. Moreover, compared with Probe A, the Probe B with near-infrared (NIR) fluorescence centered at 677 nm was successfully applied to ClO- determination in tap water and food samples as well as live cell imaging.

Emission‐Tunable Nanofluorophores through Self‐assembly of Amphiphilic Block Copolymers: toward Application in Cell Imaging

“…Exploring fluorophores that emit NIR fluorescence and have excellent water solubility, photostability and biocompatibility is in high demand for biological applications. [ 24‐29 ]…”

A Near-Infrared Fluorescent Probe for Recognition of Hypochlorite Anions Based on Dicyanoisophorone Skeleton

“…In addition, the fluorescence probing method was paid more attention as an excellent detection tool, which has realized the detection of many active species [ 19 , 20 , 21 , 22 , 23 ]. Fluorescence probes for the detection of hypochlorite anions have been reported continuously in recent years [ 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ]. Among them, some chemodosimeters using a diaminomaleonitrile group as the reaction site were used to detect hypochlorite anions, which had many advantages, such as specific recognition, high selectivity, and fast response.…”

“…Among them, some chemodosimeters using a diaminomaleonitrile group as the reaction site were used to detect hypochlorite anions, which had many advantages, such as specific recognition, high selectivity, and fast response. However, most chemodosimeters for the hypochlorite anion could hardly achieve near-infrared fluorescence emission and did not have a large Stokes shift ( Table S1 ) [ 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ]. It is well known that NIR fluorescent probes with a large Stokes shift have more advantages due to good applications in biological systems [ 47 ].…”