2024
DOI: 10.3390/vaccines12060603
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Rational Design of Lipid-Based Vectors for Advanced Therapeutic Vaccines

Yufei Ma,
Yiang Chen,
Zilu Li
et al.

Abstract: Recent advancements in vaccine delivery systems have seen the utilization of various materials, including lipids, polymers, peptides, metals, and inorganic substances, for constructing non-viral vectors. Among these, lipid-based nanoparticles, composed of natural, synthetic, or physiological lipid/phospholipid materials, offer significant advantages such as biocompatibility, biodegradability, and safety, making them ideal for vaccine delivery. These lipid-based vectors can protect encapsulated antigens and/or … Show more

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