Rational design of manganese oxide/tin oxide hybrid nanocomposite based electrochemical sensor for detection of prochlorperazine (Antipsychotic drug)

Koventhan, Chelliah; Vinothkumar, Venkatachalam; Chen, Shen‐Ming

doi:10.1016/j.microc.2021.107082

Cited by 15 publications

(6 citation statements)

References 70 publications

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“…These medications, often called psychotropic drugs, affect the way in which receptors, transporters, and enzymes function in the body. 34 Electrochemical sensors have been developed for 35 antipsychotics, [36][37][38][39][40][41][42] anti-anxiety medications, 35 antidepressants [43][44][45][46][47][48][49][50] and the mood stabilizer lithium. 51 However, electrochemical detection can be difficult because without sample preparation, there are often interfering signals.…”

Section: Electrochemical Detection Of Psychiatric Medicationsmentioning

confidence: 99%

Perspective—Electrochemical Sensors for Neurotransmitters and Psychiatrics: Steps toward Physiological Mental Health Monitoring

Zamani

Wilhelm

Furst

2022

J. Electrochem. Soc.

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Therapeutic monitoring of neurotransmitters (NTs) and psychiatric medications is essential for the diagnosis and treatment of mental illness. However, in-vivo monitoring of NTs in humans as well as continuous physiological monitoring of psychiatrics have yet to be realized. In pursuit of this goal, there has been a plethora of work to develop electrochemical sensors for both in-vivo NT monitoring as well as in-vitro detection of psychiatric medications. We review these sensors here while discussing next steps needed to achieve concurrent, continuous physiological monitoring of NTs and psychiatric medications as part of a closed-loop feedback system that guides medication administration.

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Section: Electrochemical Detection Of Psychiatric Medicationsmentioning

confidence: 99%

Perspective—Electrochemical Sensors for Neurotransmitters and Psychiatrics: Steps toward Physiological Mental Health Monitoring

Zamani

Wilhelm

Furst

2022

J. Electrochem. Soc.

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“…The electron transfer kinetics at the electrode surface were facelifted due to the electrocatalytic activity of metallic nanostructures with a noticeable shift of the redox potential toward the negative direction. Among different metallic oxide nanoparticles, the spinel ferrite-doped manganese oxide nanoparticles (FMnONPs) were selected as electrode modifiers for sensing different pharmaceutical compounds. − Herein, the research team demonstrates the fabrication and electrochemical futures of novel homemade inkjet-printed sensors modified with spinel ferrite-doped manganese oxide nanoparticles (FMnONPs) for the sensitive differential pulse voltammetric determination of BRIM in ophthalmic solutions primarily with the physiological pH value. In addition, degradation studies and molecular orbital calculations describing the tentative BRIM oxidation mechanism were also included.…”

Section: Introductionmentioning

confidence: 99%

Inkjet-Printed Sensors Based on Nanoferrite-Doped Manganese Oxide Nanoparticles for the Sensitive Differential Pulse Voltammetric Determination of Brimonidine

Al-bonayan,

Alrefaee,

Alessa

et al. 2024

ACS Omega

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The present study described the construction and the electrochemical futures of a novel inject-printed electrochemical sensor based on spinel ferrite-doped manganese oxide nanoparticles (FMnONPs) for the sensitive differential pulse voltammetric quantification of brimonidine (BRIM) in ophthalmic solutions. At the optimized electroanalytical parameters, calibration graphs were linear within the BRIM concentration range of 24− 3512 ng mL −1 and recorded a detection limit value of 8.21 ng mL −1 . Cyclic voltammograms recorded at different scan rates indicated an adsorption-reaction mechanism for the electrooxidation of BRIM at the electrode surface with the involvement of two electrons and one proton based on the oxidation of the fivemembered ring nitrogen atom as recommended by the molecular orbital calculations. The enhanced performance of the introduced inkjet-printed sensors integrated with FMnONPs encourages their application for monitoring BRIM residues in ophthalmic solutions and biological fluids in the presence of BRIM degradation products and other interferents for diverse quality control applications.

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“…Consequently, it is vital to develop a convenient and highly efficient approach for the selective detection of DA and UA. Compared to other detection methods such as chromatography, fluorescence and spectrophotometry, the electrochemical method offers the advantages of high sensitivity, quick response times, cost-effectiveness, and convenience, and has aroused more and more attention [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

ZnO-CeO2 Hollow Nanospheres for Selective Determination of Dopamine and Uric Acid

Zhang,

Yan,

Chen

et al. 2024

Molecules

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ZnO-CeO2 hollow nanospheres have been successfully synthesized via the hard templating method, in which CeO2 is used as the support skeleton to avoid ZnO agglomeration. The synthesized ZnO-CeO2 hollow nanospheres possess a large electrochemically active area and high electron transfer owing to the high specific surface area and synergistic effect of ZnO and CeO2. Due to the above advantages, the resulting ZnO-CeO2 hollow spheres display high sensitivities of 1122.86 μA mM−1 cm−2 and 908.53 μA mM−1 cm−2 under a neutral environment for the selective detection of dopamine and uric acid. The constructed electrochemical sensor shows excellent selectivity, stability and recovery for the selective analysis of dopamine and uric acid in actual samples. This study provides a valuable strategy for the synthesis of ZnO-CeO2 hollow nanospheres via the hard templating method as electrocatalysts for the selective detection of dopamine and uric acid.

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Rational design of manganese oxide/tin oxide hybrid nanocomposite based electrochemical sensor for detection of prochlorperazine (Antipsychotic drug)

Cited by 15 publications

References 70 publications

Perspective—Electrochemical Sensors for Neurotransmitters and Psychiatrics: Steps toward Physiological Mental Health Monitoring

Perspective—Electrochemical Sensors for Neurotransmitters and Psychiatrics: Steps toward Physiological Mental Health Monitoring

Inkjet-Printed Sensors Based on Nanoferrite-Doped Manganese Oxide Nanoparticles for the Sensitive Differential Pulse Voltammetric Determination of Brimonidine

ZnO-CeO2 Hollow Nanospheres for Selective Determination of Dopamine and Uric Acid

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