Rational diagnostic advance of Kushtha (integumentary diseases) by a preliminary arbitrary grading system based on Ayurveda fundamental principles

Nath, Rupashri; Mandal, Sisir Kumar; Mahajon, Bidhan

doi:10.31254/jsir.2019.8202

Cited by 3 publications

(1 citation statement)

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“…In Ayurveda, skin disorders are included under the heading of kustha and Kshudraroga [15][16][17] . Causative factors where pittakaraka ahara, vihara and manasika karanas (Psychological factors) like krodha, shoka, bhaya and ayasa 118 .…”

Section: Discussionmentioning

confidence: 99%

The Effect of Nasal Administration on the Management of Melasma -A Case Study

Kalyani

Manu

2022

Int J Life Sci Pharm Res

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Melasma is commonest among hyperpigmantation diseases which presents as irregularly shaped, but often distinctly defined as blotches of light to dark-brown pigmentation. It is a very common chronic disorder usually seen in women of childbearing age which is a frustrating condition to the women. There are 12.3% to 19.4% of world population suffering with this problem. Vyanga is one of the kshudra roga and is explained by Acharya Sushruta as painless thin brown patches over face. While considering the pathogenesis of vyanga, involvement of pitta is more and it is a rakta pradoshaja vyadhi. Depending on the pathogenesis and asrayaasrayi bhava of doshas involved, nasya(nasal route) is mainly indicated. By doing the nasya (nasal route) it it benefits in relieving the excess (pitta vriddi) pitta and also helps in varna prasadana(complexion). In this single case study, pratimarsha nasya was administered for 30 days continuously. The assessment criterias were noted before and after the treatment. Subjective parameters i.e Mukhamagatya mandalam (patches), Shyava varna(pigmentation), Kandu (itching), Parusha sparsha(dry skin) are the chief complaints of Vyanga and objective parameters such as MASI (Melasma area seviarity index). Assessments are done before and after the treatment. Symptoms of Melasma (Vyanga) decreased and it showed clinical progressiveness of the treatment given. In our study we found Color (pigmentation) of the leision had shown improvement .

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Section: Discussionmentioning

confidence: 99%

The Effect of Nasal Administration on the Management of Melasma -A Case Study

Kalyani

Manu

2022

Int J Life Sci Pharm Res

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An Evidence Based Diminutive Model for Diagnosis of Nilika-Type of Skin Disorder in Ayurveda

Nath

Mandal

2020

Global Journal for Research Analysis

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The disease Nilika is a type of kshudra kustha (group of skin disorders), mentioned in Ayurveda. It may manifests with various sign and symptoms like Krishna (Blackish discoloration), Nirujatanu (painless thin lesion) that may generally manifests in Gatra mukha i.e. whole body and face. In Ayurveda there is no such standard parameter to diagnose this diseases easily. The present endeavor has been made to develop an arbitrary grading system based on classical diagnostic outline mentioned in classical texts of Ayurveda. The effort has also given to understand the savagery of this disease with the help of its elementary sign and symptoms. All the classical metaphors available on Nilika mentioned in classical texts were analyzed and envision features were documented in the structure of photography to diagnose the disease precisely. Further validation of this groundwork of grading system should be confirmed in large scale clinical study.

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A Study Protocol of a Prospective, Open-label, Single-arm, Clinical Trial to Evaluate the Efficacy of Classical Ayurveda Medicines in the Management of Vicharchika (Atopic Eczema)

Rao¹,

Sharma²,

Mahajon³

2019

Journal of Research in Ayurvedic Sciences

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Background: In Ayurveda, Vicharchika (atopic eczema, AE) has been discussed under the heading of Kshudra kustha. It is a variety of inflammatory skin disorders diagnosed as a chronic, widespread, noninfective inflammatory condition that causes severe pruritus, erythema with variable degree of exudates and scaling, which can impact at any age. The etiology of AE is complex and not fully understood. Although the traditional Ayurveda medicine is used as an alternative therapy for AE, available evidence relating to its effectiveness and mechanism are not fully implicit. Hence, a protocol of a prospective, multicenter, single-arm, open-label clinical trial using traditional Ayurveda medicine to investigate the effectiveness, mechanism, and safety for patients with Vicharchika (eczema) is being reported. Materials and methods: This is a multicenter, single-arm, open-label clinical trial to evaluate the safety and efficacy of traditional Ayurveda formulations Panchatikta Ghrita and Nalpamaradi Taila in the management of Vicharchika (eczema). A total of 120 patients with Vicharchika (eczema) will be selected based on the inclusion and exclusion criteria. All the patients will be provided with classical Ayurvedic formulation, i.e., Panchatikta Ghrita 6 g orally twice daily before food and oil Nalpamaradi Taila 20 mL twice daily externally on the affected skin. Each participant will undergo a 12-week treatment period and a follow-up after 4 weeks. A total of seven visits will be scheduled for each participant: 1 visit each in week 0, week 2, week 4, week 6, week 8, week 10, and week 12. The primary outcome will be measured by the assessment of change in eczema area severity index (EASI) score before and after the recommended therapy. The secondary outcomes will be measured by—changes in clinical sign and symptoms per the Ayurvedic classics; changes in patient-oriented eczema measure (POEM) and changes in dermatology life quality index (DLQI) questionnaire. Therapeutic mechanism outcomes, safety outcomes, and end point outcomes will also be assessed. Discussion: Protocol was designed with projected outcome as better clinical deliverables and safety profile in Vicharchika patients and reduced relapse rate of disease during post treatment period. If found effective, the selected drug will be listed in the management protocol of Vicharchika at clinical practice level in terms of better efficacy, safety, and cost-effective treatment. The selected drug may lead to a step ahead of better understanding and management of additional skin disorders. Trial registration: Trial has been registered under clinical trials registry-India (CTRI); the registration number for this trial is CTRI/2019/12/022236.

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Rational diagnostic advance of Kushtha (integumentary diseases) by a preliminary arbitrary grading system based on Ayurveda fundamental principles

Cited by 3 publications

References 0 publications

The Effect of Nasal Administration on the Management of Melasma -A Case Study

The Effect of Nasal Administration on the Management of Melasma -A Case Study

An Evidence Based Diminutive Model for Diagnosis of Nilika-Type of Skin Disorder in Ayurveda

A Study Protocol of a Prospective, Open-label, Single-arm, Clinical Trial to Evaluate the Efficacy of Classical Ayurveda Medicines in the Management of Vicharchika (Atopic Eczema)

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