Rational Use of Lasmiditan for Acute Migraine Treatment in Adults: A Narrative Review

Ferrari, Anna; Rustichelli, Cecilia

doi:10.1016/j.clinthera.2021.01.020

Search citation statements

Order By: Relevance

Paper Sections

Select...

Lasmiditan2

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(2 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lasmiditan is primarily eliminated via metabolism, whereas renal excretion plays only a minor role in drug clearance. 17 When administered orally, lasmiditan reduced migraine pain and the most bothersome symptoms within two hours. [18][19][20] Compared to placebo, treatment-emergent related adverse events (TEAEs) were reported more frequently within 48 hours in patients assigned to lasmiditan.…”

Section: Lasmiditanmentioning

confidence: 99%

“…Taking lasmiditan with a high-fat meal may prolong the time to reach the maximum plasma concentration, but it is not expected to be clinically significant. 17 The biological half-life of lasmiditan is 5.7 h, the binding to blood proteins is around 60%. Lasmiditan is primarily eliminated via metabolism, whereas renal excretion plays only a minor role in drug clearance.…”

Section: Lasmiditanmentioning

confidence: 99%

See 1 more Smart Citation