Re: Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Lachmann, Robert; Brückmann, A

doi:10.1002/uog.23124

Ultrasound in Obstet & Gyne

2021

DOI: 10.1002/uog.23124

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Re: Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Robert Lachmann

A Brückmann

Abstract: Linked article: This Correspondence comments on Lakshmy et al. Click https://obgyn.onlinelibrary.wiley.com/doi/full/10.1002/uog.21931 to view the article.

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2023

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Ultrasound Detection of Fetal Palate Development in the Early Stages of the Second Trimester and Its Clinical Application

Liao,

Liu,

Zhang

et al. 2023

The Cleft Palate Craniofacial Journal

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Objective To establish normal values of palatal bone growth in fetuses at different gestational weeks in the early stages of the second trimester and to explore the clinical application value of the four-step ultrasound screening method for fetal cleft lip and palate. Design A prospective study of prenatal ultrasound screening. Setting Secondary maternal and child health institutions. Patients 300 fetuses of 12 to 20 +6 weeks gestation without cleft lip and/or palate; 8538 fetuses at high risk of cleft lip and palate with malformations or karyotypic abnormalities. Interventions None. Main Outcome Measures palatomandibular diameter (PMD) and transverse palatal diameter was measured and establish their typical values. Results (1) There is a typical “superimposed line” sign in the median sagittal section of the typically developing fetal face from 12 to 20+6 weeks of gestation. (2) The PMD and hard palate transverse diameter of fetuses from 12 to 20+6 weeks of gestation increased linearly with time. (3) Among 8538 high-risk fetuses, 21 cases of cleft lip and palate were diagnosed by the four-step ultrasound screening method in the early stages of the second trimester. Conclusions The median sagittal section of the typically developing fetal face in the early stages of the second trimester presents a typical “superimposed line” sign, and the PMD and transverse palatal diameter increase with time. The four-step ultrasound screening method for fetal cleft lip and palate in the early stages of the second trimester has high clinical application value.

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Ultrasound Detection of Fetal Palate Development in the Early Stages of the Second Trimester and Its Clinical Application

Liao,

Liu,

Zhang

et al. 2023

The Cleft Palate Craniofacial Journal

View full text Add to dashboard Cite

show abstract

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Re: Absent ‘superimposed‐line’ sign: novel marker in early diagnosis of cleft of fetal secondary palate

Abstract: Linked article: This Correspondence comments on Lakshmy et al. Click https://obgyn.onlinelibrary.wiley.com/doi/full/10.1002/uog.21931 to view the article.

Cited by 1 publication

References 3 publications

Ultrasound Detection of Fetal Palate Development in the Early Stages of the Second Trimester and Its Clinical Application

Ultrasound Detection of Fetal Palate Development in the Early Stages of the Second Trimester and Its Clinical Application

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