Re: de Assis et al. “Effects of Prostatic Artery Embolization on the Dynamic Component of Benign Prostate Hyperplasia as Assessed by Ultrasound Elastography: A Pilot Series”

Moschouris, Hippocrates; Stamatiou, Konstantinos; Dimakis, Andreas; Malagari, Katerina

doi:10.1007/s00270-019-02272-z

Cited by 4 publications

(2 citation statements)

References 5 publications

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“… 28 , 29 Promisingly several studies have confirmed an associated reduction in the elastic modulus of the prostate following PAE measured by several imaging techniques including magnetic resonance imaging (MRI). 30 , 31 Alternatively, this reduction in stiffness could be sequelae of infarct remodeling with fibroblasts which reduce the prostatic stiffness, 32 but either way, a reduction in the dynamic obstructive component is clearly a feasible action of PAE.…”

Section: Clinical and Research Consequencesmentioning

confidence: 99%

Comprehensive Review on Current Controversies and Debate in Prostate Artery Embolization

Maclean¹,

Bryant²,

Vigneswaran³

et al. 2022

Turkish Journal of Urology

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Prostate artery embolization is emerging as one of the most effective therapies amidst a new era of minimally invasive benign prostate hyperplasia treatment and technology. However, several current controversies remain unanswered which could impact the widespread adoption of this novel and unique transarterial (rather than transurethral) intervention. This is reflected in the differences between the UK (NICE), European (EAU), and American (AUA) guidelines, the latter of which only recommends the use of prostate artery embolization in a clinical trial setting. The main issues include questions over the duration of symptom response, cost-effectiveness, mechanism of action, patient selection, and other procedural technical considerations. These factors are the most pressing faced by proponents of prostate artery embolization, and we seek to highlight why their resolution is important to ensure men with benign prostate hyperplasia seeking a minimally invasive solution are optimally informed and most effectively managed.

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Section: Clinical and Research Consequencesmentioning

confidence: 99%

Comprehensive Review on Current Controversies and Debate in Prostate Artery Embolization

Maclean¹,

Bryant²,

Vigneswaran³

et al. 2022

Turkish Journal of Urology

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“…Of note, no significant elastographic changes were observed in the peripheral zone. Another small group of PAE-patients were studied with t.r.-strain elastography, a semi-quantitative US-elastographic technique which measures tissue deformation caused by mechanical stimuli from the US-probe[ 25 ]. By comparing the tissue before and after compression, the degree of local tissue deformation (strain) is estimated in real time and projected on a color map.…”

Section: Us-elastographymentioning

confidence: 99%

Sonographic evaluation of prostatic artery embolization: Far beyond size measurements

Moschouris

Dimakis

Anagnostopoulou

et al. 2020

WJR

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Prostatic artery embolization (PAE) has gained acceptance as a minimally invasive, safe and effective treatment of symptomatic benign prostatic hyperplasia. Radiologic imaging is an indispensable part of post-interventional evaluation of PAE and serves both clinical and investigational purposes. In this context, ultrasonography (US) has a central and multifaceted role. Gray-scale US is routinely utilized for measurement of significant outcome parameters (prostatic volume, intra-vesical prostatic protrusion and post-void residual volume) before and after PAE. Improvement of these parameters may become more obvious one-month post-PAE, or later. Contrast-enhanced US (CEUS) with intravenous administration of a second-generation echo-enhancer can demonstrate prostatic infarcts (as enhancement defects) immediately post-PAE and monitor their resolution over time. The volume of prostatic infarcts can also be measured and compared to prostatic volume. Prostatic infarction is a definite sign of the local efficacy of PAE and a predictor of prostate shrinkage and (at least in some patients) of clinical success. CEUS can also be performed intraoperatively in the angio-suite, for on-site evaluation of the ischemic effect; a variation of this technique, with intraarterial (instead of intravenous) administration of diluted echo enhancer, can also be applied intraoperatively, to map the embolized territory and to prevent non-target embolization. Initial experience with US-elastographic techniques (shear-wave and strain elastography) has shown that they can detect and quantify the improvement of tissue elasticity post-PAE, thus providing new insights into the therapeutic mechanisms of this treatment. With utilization of high-end equipment, experience and standardized imaging protocols, US could be the primary modality for imaging evaluation of PAE.

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Role of Ultrasound Elastography in Patient Selection for Prostatic Artery Embolization

Assis

Moreira

Carnevale

et al. 2021

Journal of Vascular and Interventional Radiology

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Re: de Assis et al. “Effects of Prostatic Artery Embolization on the Dynamic Component of Benign Prostate Hyperplasia as Assessed by Ultrasound Elastography: A Pilot Series”

Cited by 4 publications

References 5 publications

Comprehensive Review on Current Controversies and Debate in Prostate Artery Embolization

Comprehensive Review on Current Controversies and Debate in Prostate Artery Embolization

Sonographic evaluation of prostatic artery embolization: Far beyond size measurements

Role of Ultrasound Elastography in Patient Selection for Prostatic Artery Embolization

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