Re-evaluation and modification of the Stuivenberg Hospital Acute Renal Failure (SHARF) scoring system for the prognosis of acute renal failure: an independent multicentre, prospective study

Lins, Robert; Elseviers, Monique; Daelemans, R.; Arnouts, Paul; Billiouw, Jean-Marie; Couttenye, Marie-Madeleine; Gheuens, Eric; Rogiers, Peter; Rutsaert, R.; Niepen, Patricia Van der; Broe, Marc E. De

doi:10.1093/ndt/gfh364

Cited by 67 publications

(43 citation statements)

References 20 publications

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“…Multiple AKI severity scores have been published in the literature and are listed in table 1[16,17,18,19,20,21,22,23,24,25,26,27]. Most of these scores were developed in a single center, or if multicentric, they were confined to a single country.…”

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

“…Most of these scores were developed in a single center, or if multicentric, they were confined to a single country. Although one study was conducted in a multicenter setting [24], this study was originally conducted as a randomized controlled study of atrial natriuretic peptide for AKI [28] and the sample size was smaller than other more recently conducted studies[25,26,27]. The three AKI severity scores, which are based on larger samples than others and have been recently published, are discussed below.…”

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

“…Multivariate logistic regression analysis was used to generate the score. Using their population, they compared the AUROC and Hosmer-Lemeshow goodness-of-fit of their score with several general severity scores and kidney specific severity scores [19, 20, 23, 24, 26, 29]. They found that their score had the best discrimination (AUROC of 0.832) and calibration ability among all scores they tested.…”

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

“…The SHARF (Stuivenberg Hospital Acute Renal Failure) II score [26] was a modified version of the previously published kidney-specific severity score [29]. Originally, these investigators generated a score based on data from 197 patients in a single center in Belgium from March 1996 to April 1997.…”

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

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Outcome Prediction for Patients with Acute Kidney Injury

Uchino¹

2008

Nephron Clin Pract

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Background/Aims: To review the currently available severity scores to predict outcome of acute kidney injury (AKI) patients, to discuss the problems with such scores, and to provide information for the development of more accurate AKI severity scores in the future. Methods: Literature review and multivariate analysis using a large international database for AKI. Results: Although general severity scores have good discrimination and calibration abilities to predict outcome of critically ill patients, the accuracy of these systems for AKI patients has been questioned. To improve prediction ability, multiple AKI severity scores have been published in the literature. However, most of these scores were developed and tested in a single center, or if multicentric, they were confined to a single country. Seven variables (mechanical ventilation, bilirubin, age, oliguria, hypotension, sepsis and platelet count) are often found as common risk factors in these severity scores and should be included in future AKI severity scores. Although several studies have consistently reported that both low creatinine and high urea at the start of RRT are related to worse outcome in AKI patients, they might not improve prediction ability. Conclusion: Using available information and a large database collected internationally, a more accurate score for AKI is likely to be developed.

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Section: Aki-specific Severity Scoresmentioning

confidence: 99%

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

Section: Aki-specific Severity Scoresmentioning

confidence: 99%

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Outcome Prediction for Patients with Acute Kidney Injury

Uchino¹

2008

Nephron Clin Pract

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“…In a second phase, the SHARF score was tested in a multicenter study. After adaptation based on multivariate analysis, the SHARF score was tested and proved to be useful in different settings for comparing groups of patients and centers (17). This multicenter SHARF4 study investigated different treatment options (conservative versus RRT) in patients with AKI stratified according to severity of disease by SHARF score.…”

mentioning

confidence: 99%

Outcome of Acute Kidney Injury with Different Treatment Options

Berendoncks

Elseviers

Lins

2010

Clinical Journal of the American Society of Nephrology

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Results: The baseline population consisted of 595 AKI patients. Mortality rates were 23.0 and 7.6%, respectively, during the first and second year after discharge. Total mortality increased from 50.7% at discharge to 65.7% 2 years after AKI and was not related to disease severity or treatment modality offered during hospitalization. Two hundred four survivors could be visited at home. Mean serum creatinine did not differ between discharge and follow-up. CCI was only related with age. SF-36 scores were negatively correlated with CCI, age, and body mass index, but not with disease severity, renal function, or dialysis modality.Conclusions: Long-term outcome of AKI consists of a high additional mortality unrelated to treatment modality offered during hospitalization, varying evolution of renal recovery, and many comorbidities, but a mental health at the same level as the general population.

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