Re-evaluation of cellulose acetate polymer: angiographic findings and histological studies

Yang, Xinjian; Wu, Zhongxue; Li, Youxiang; Tang, Jun; Sun, Yu; Zuo-qin, Liu; Yin, Ke

doi:10.1016/s0090-3019(00)00331-1

Cited by 9 publications

(5 citation statements)

References 13 publications

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“…Introduction of coils with complex shapes and 3-dimensional structures, ultrasoft coils, 302 liquid polymer techniques, 303 bioactive or coated coils, the development of techniques using balloons, 304 -307 and intravascular stents 308 -314 to support coil occlusion are examples of improvements that have broadened the indications for coil embolization. New adjuvant techniques may also carry greater procedural risks that will influence outcome.…”

Section: Surgical and Endovascular Methods For Treatment Of Ruptured mentioning

confidence: 99%

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

Bederson¹,

Connolly²,

Batjer³

et al. 2009

Stroke

1,165

488

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Section: Surgical and Endovascular Methods For Treatment Of Ruptured mentioning

confidence: 99%

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

Bederson¹,

Connolly²,

Batjer³

et al. 2009

Stroke

1,165

488

View full text Add to dashboard Cite

“…Growth and/or rupture of experimental aneurysms were found in three types of models: sidewall (n = 12) [3,8,[13][14][15][16][17][18][19][20][21][22], bifurcation stump (n = 6) [14,[23][24][25][26][27], and terminal (n = 3) [28][29][30]. Most frequent growth was reported in rats (n = 6) [8,14,16,[23][24][25], followed by rabbits (n = 4) [13,21,26,29], dogs (n = 4) [19,27,28,30], swine (n = 5) [3,17,18,20,22], and sheep (n = 1) [15]. Except for two studies reporting growth and rupture within the abdominal cavity (abdominal aortic artery; n = 2) [8,16] all other aneurysms were located at the neck of the animal (common carotid artery; n = 18).…”

Section: Resultsmentioning

confidence: 99%

Saccular Aneurysm Models Featuring Growth and Rupture: A Systematic Review

et al. 2020

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Background. Most available large animal extracranial aneurysm models feature healthy non-degenerated aneurysm pouches with stable long-term follow-ups and extensive healing reactions after endovascular treatment. This review focuses on a small subgroup of extracranial aneurysm models that demonstrated growth and potential rupture during follow-up. Methods. The literature was searched in Medline/Pubmed to identify extracranial in vivo saccular aneurysm models featuring growth and rupture, using a predefined search strategy in accordance with the PRISMA guidelines. From eligible studies we extracted the following details: technique and location of aneurysm creation, aneurysm pouch characteristics, time for model creation, growth and rupture rate, time course, patency rate, histological findings, and associated morbidity and mortality. Results. A total of 20 articles were found to describe growth and/or rupture of an experimentally created extracranial saccular aneurysm during follow-up. Most frequent growth was reported in rats (n = 6), followed by rabbits (n = 4), dogs (n = 4), swine (n = 5), and sheep (n = 1). Except for two studies reporting growth and rupture within the abdominal cavity (abdominal aortic artery; n = 2) all other aneurysms were located at the neck of the animal. The largest growth rate, with an up to 10-fold size increase, was found in a rat abdominal aortic sidewall aneurysm model. Conclusions. Extracranial saccular aneurysm models with growth and rupture are rare. Degradation of the created aneurysmal outpouch seems to be a prerequisite to allow growth, which may ultimately lead to rupture. Since it has been shown that the aneurysm wall is important for healing after endovascular therapy, it is likely that models featuring growth and rupture will gain in interest for preclinical testing of novel endovascular therapies.

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“…Optimum micro-catheter performance is required to retain embolic polymer while giving moderate strength, traceability, and stability. [11] Yang et al [62] concluded that cellulose acetate is not an ideal embolic for intracranial aneurysms as it severely damages vessels with a strong chemo-corrosive effect and might cause aneurysm rupture. Mordasini et al [63] compared imaging characteristics of the polymeric coil with platinum one in vitro with an aneurysm model and in vivo with experimentally created rabbit carotid bifurcation aneurysm.…”

Section: Single Component Polymersmentioning

confidence: 99%

“…[ 11 ] Yang et al. [ 62 ] concluded that cellulose acetate is not an ideal embolic for intracranial aneurysms as it severely damages vessels with a strong chemo‐corrosive effect and might cause aneurysm rupture. Mordasini et al.…”

Section: Single Component Polymersmentioning

confidence: 99%

Single Component Polymers, Polymer Blends, and Polymer Composites for Interventional Endovascular Embolization of Intracranial Aneurysms

Karadeli,

Kuram

2023

Macromolecular Bioscience

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Intracranial aneurysm is the abnormal focal dilation in brain arteries. When untreated, it can enlarge to rupture points and account for subarachnoid hemorrhage cases. Intracranial aneurysms can be treated by blocking the flow of blood to the aneurysm sac with clipping of the aneurysm neck or endovascular embolization with embolics to promote the formation of the thrombus. Coils or an embolic device are inserted endovascularly into the aneurysm via a micro‐catheter to fill the aneurysm. Many embolization materials have been developed. An embolization coil made of soft and thin platinum wire called the “Guglielmi detachable coil” (GDC) enables safer treatment for brain aneurysms. However, patients may experience aneurysm recurrence because of incomplete coil filling or compaction over time. Unsatisfactory recanalization rates and incomplete occlusion are the drawbacks of endovascular embolization. So, the fabrication of new medical devices with less invasive surgical techniques is mandatory to enhance the long‐term therapeutic performance of existing endovascular procedures. For this aim, the current article reviews polymeric materials including blends and composites employed for embolization of intracranial aneurysms. Polymeric materials used in embolic agents, their advantages and challenges, results of the strategies used to overcome treatment, and results of clinical experiences are summarized and discussed.

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Re-evaluation of cellulose acetate polymer: angiographic findings and histological studies

Cited by 9 publications

References 13 publications

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

Saccular Aneurysm Models Featuring Growth and Rupture: A Systematic Review

Single Component Polymers, Polymer Blends, and Polymer Composites for Interventional Endovascular Embolization of Intracranial Aneurysms

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