Re-evaluation of Mannheim prognostic index in perforative peritonitis: Prognostic role of advanced age. A prospective cohort study

Neri, Alessandro; Marrelli, Daniele; Scheiterle, M.; Mare, Giulio Di; Sforza, Simone; Roviello, Franco

doi:10.1016/j.ijsu.2014.11.035

Cited by 17 publications

(35 citation statements)

References 18 publications

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“…and mortality[ 29 - 31 ]. Finally, we did not find that age influenced mortality, but the population we studied was older than that of other studies[ 15 , 32 , 33 ]. Controversies exist regarding age as a risk factor for mortality in ICUs, and factors other than age itself, such as previous comorbidities and/or frailty, may have a better prognostic significance[ 34 , 35 ].…”

Section: Discussioncontrasting

confidence: 61%

Risk factors for mortality in postoperative peritonitis in critically ill patients

Launey¹,

Duteurtre²,

Larmet³

et al. 2017

WJCCM

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AIMTo identify the risk factors for mortality in intensive care patients with postoperative peritonitis (POP).METHODSThis was a retrospective analysis using a prospective database that includes all patients hospitalized in a surgical intensive care unit for POP from September 2006 to August 2011. The data collected included demographics, comorbidities, postoperative severity parameters, bacteriological findings, adequacy of antimicrobial therapy and surgical treatments. Adequate source control was defined based on a midline laparotomy, infection source control and intraoperative peritoneal lavage. The number of reoperations needed was also recorded.RESULTSA total of 201 patients were included. The overall mortality rate was 31%. Three independent risk factors for mortality were identified: The Simplified Acute Physiological II Score (OR = 1.03; 95%CI: 1.02-1.05, P < 0.001), postoperative medical complications (OR = 6.02; 95%CI: 1.95-18.55, P < 0.001) and the number of reoperations (OR = 2.45; 95%CI: 1.16-5.17, P = 0.015). Surgery was considered as optimal in 69% of the cases, but without any significant effect on mortality.CONCLUSIONThe results from the large cohort in this study emphasize the role of the initial postoperative severity parameters in the prognosis of POP. No predefined criteria for optimal surgery were significantly associated with increased mortality, although the number of reoperations appeared as an independent risk factor of mortality.

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Section: Discussioncontrasting

confidence: 61%

Risk factors for mortality in postoperative peritonitis in critically ill patients

Launey¹,

Duteurtre²,

Larmet³

et al. 2017

WJCCM

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“…Multiple Organ Failure (MOF) represents the fatal evolution of the peritonitis (4). In Western countries, the increasing number of older patients worsen the prognosis of surgical pathologies often also for relevant comorbidities presence (38).…”

Section: Discussionmentioning

confidence: 99%

Mannheim Peritonitis Index (MPI) and elderly population: prognostic evaluation in acute secondary peritonitis

Salamone¹,

Licari²,

Falco³

et al. 2016

Gchir

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“…For all IAIs, the presence of sepsis or septic shock is a generic prognostic feature and defines a disease process that has become systemic, rather than a localized disease process. Several disease specific scores exist for various organ-related IAIs (appendicitis, diverticulitis, perforated ulcers) [49][50][51][52], for which none have good accuracy, prediction ability, nor validity and generalizability.…”

Section: Statementmentioning

confidence: 99%

Management of Intra-Abdominal Infections

Moore

2016

Common Problems in Acute Care Surgery

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This paper reports on the consensus conference on the management of intra-abdominal infections (IAIs) which was held on July 23, 2016, in Dublin, Ireland, as a part of the annual World Society of Emergency Surgery (WSES) meeting. This document covers all aspects of the management of IAIs. The Grading of Recommendations Assessment, Development and Evaluation recommendation is used, and this document represents the executive summary of the consensus conference findings.

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Re-evaluation of Mannheim prognostic index in perforative peritonitis: Prognostic role of advanced age. A prospective cohort study

Abstract: Age older than 80 years is strongly related to major increase in mortality rates and should be taken into account together with the MPI score in planning the surgical approach and the post-operative care.

Cited by 17 publications

References 18 publications

Risk factors for mortality in postoperative peritonitis in critically ill patients

Risk factors for mortality in postoperative peritonitis in critically ill patients

Mannheim Peritonitis Index (MPI) and elderly population: prognostic evaluation in acute secondary peritonitis

Management of Intra-Abdominal Infections

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