Re-examining Vaccine Staggering Within Hesitancy Frameworks

Rutschman, Ana Santos; Wiemken, Timothy

doi:10.3389/fimmu.2021.662814

Cited by 2 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…14 However, accurate measurement of influenza vaccination status in the United States is a challenge because many persons obtain vaccinations outside their healthcare system, 15 and we lack a national immunization registry. 16 Overall, the dose-response relationship between vaccination and dementia has not been well described.…”

Section: Introductionmentioning

confidence: 99%

“…Our own analysis of Veterans Health Administration (VHA) data suggests reduced dementia risk requires ≥6 annual influenza vaccines as compared with none 14 . However, accurate measurement of influenza vaccination status in the United States is a challenge because many persons obtain vaccinations outside their healthcare system, 15 and we lack a national immunization registry 16 . Overall, the dose–response relationship between vaccination and dementia has not been well described.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of rates of dementia among older adult recipients of two, one, or no vaccinations

Wiemken

Salas

Morley

et al. 2021

J American Geriatrics Society

Self Cite

View full text Add to dashboard Cite

Background: Multiple types of vaccinations are associated with lower risk for dementia, but it is not known if receiving more than one vaccination type is associated with a greater decrease in incident dementia as compared with receiving only one type. We determined if dementia risk is lowest in patients who receive both herpes zoster (HZ) and tetanus, diphtheria, pertussis (Tdap) vaccinations as compared with receipt of only one or the other type of vaccination.Methods: Primary analysis in a Veterans Health Administration (VA) cohort was replicated in private sector medical claims data. Eligible patients were ≥65 years of age and free of dementia for 2 years prior to baseline (VHA n = 80,070; MarketScan n = 129,200). At index, patients either had both HZ and Tdap, only HZ, only Tdap, or neither vaccination. Confounding was controlled with generalized boosted propensity scores and inverse probability of treatment weighting. Competing risk (VHA) and Cox proportional hazard (MarketScan) models estimated the association between vaccination status and incident dementia.Results: VHA patients' mean age was 76.8 ± 7.6 years, 4.4% were female and 90.9% were White, and MarketScan patients' mean age was 70.5 ± 5.9 and 65.4% were female. In both cohorts, having both HZ and Tdap vaccinations compared with no vaccination was significantly associated with lower dementia risk (VHA HR = 0.50; 95% CI: 0.43-0.59; MarketScan HR = 0.58; 95% CI: 0.38-0.89). In both cohorts, compared with neither vaccination, patients with only one or the other vaccination types had a significantly lower risk for dementia. Incident dementia was lower in patients with both vaccinations versus only one vaccination type.The views expressed do not necessarily reflect those of the Veterans Health Administration.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of rates of dementia among older adult recipients of two, one, or no vaccinations

Wiemken

Salas

Morley

et al. 2021

J American Geriatrics Society

Self Cite

View full text Add to dashboard Cite

show abstract

“…19 In a sense, it is a priority to deliver timely routine vaccinations for ageappropriate children, given the cumulative susceptible individuals, endemic transmission and imported measles cases sparking outbreaks. 20 Generally, factors underlying timely routine vaccinations are multifaceted, including factors of vaccination service demander (eg, health belief on vaccination), 21 vaccination service provider (eg, professional competency in vaccination services), 22 the performance of immunisation programmes in health system (eg, vaccine supply, financial support and administration of vaccinations), 23 access to vaccination services 24 25 and vaccination-related health system. 26 Furthermore, imperfect vaccination service mode or policy may be one of the causes of untimely vaccination and non-vaccination.…”

Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

Health system barriers to timely routine measles vaccinations in rural southwest China: a qualitative study on the perspectives of township vaccination professionals and village doctors

Cheng,

Lan,

Geater

et al. 2023

BMJ Open

View full text Add to dashboard Cite

ObjectivesA well-functioning health system ensures timely routine measles vaccinations for age-appropriate children, minimising measles risk. However, there is limited knowledge about the impact of the performance of immunisation programmes in health systems on the timeliness of measles vaccination. This study aimed to identify health system barriers to timely routine measles vaccination in rural southwest China, integrating the perspectives of township vaccination professionals and village doctors.Design, setting and participantsQualitative study among township vaccination professionals and village doctors in rural Guangxi, southwest China.Methods20 focus group discussions (FGDs) at township level and 120 in-depth interviews (IDIs) at village level, based on a four-theme framework. We used convenience sampling to recruit 60 township vaccination professionals and 120 village doctors in 2015. Instruments used were a semistructured questionnaire and interview outlines. We collected township and village-level data focusing on themes of health resources allocation, pattern of vaccination services, management and supervision of vaccination services, and perceptions of vaccination policy. The FGDs and IDIs were audio-recorded and transcribed. Braun and Clarke’s thematic analysis approach was adopted to synthesise findings into meaningful subthemes, narrative text and illustrative quotations.ResultsThe health system barriers to timely routine vaccinations were explored across four themes. Barriers in the health resources allocation theme comprised (1) inadequacy of vaccination-related human resources (eg, lack of township vaccination professionals and lack of young village doctors), and (2) incompatible and non-identical information system of vaccination services across regions. Barriers in the pattern of vaccination services theme included inflexible vaccination services models, for example, routine vaccination services being offered monthly on fixed vaccination days, limited numbers of vaccination days per month, vaccination days being set on non-local market days, vaccination days being clustered into a specific period and absence of formal vaccination appointments. Ineffective economic incentive mechanism was identified as a barrier in the management and supervision of vaccination services theme. Low-degree participation of village doctors in routine vaccination services was identified as a barrier in the perceptions of vaccination policy theme.ConclusionsWe encourage policymakers and stakeholders to apply these findings to improve the timeliness of routine vaccination. Barriers to timely routine vaccination include inadequate allocation of vaccination-related resources and inflexible vaccination service delivery models. Financial and non-financial incentives should be used to retain and recruit vaccination professionals and village doctors. Strengthening information systems with unified data standards enables cross-regional data exchange. Optimising immunisation services and rationalising vaccination days could eliminate health system barriers and improve vaccination timeliness in rural China.

show abstract

Re-examining Vaccine Staggering Within Hesitancy Frameworks

Cited by 2 publications

References 10 publications

Comparison of rates of dementia among older adult recipients of two, one, or no vaccinations

Comparison of rates of dementia among older adult recipients of two, one, or no vaccinations

Health system barriers to timely routine measles vaccinations in rural southwest China: a qualitative study on the perspectives of township vaccination professionals and village doctors

Contact Info

Product

Resources

About