Re-Hospitalization in First Six Months After Live Related Renal Transplantation: Risk Factors, Burden, Causes and Outcomes

Abstract

The aim of our study was to evaluate the incidence, causes, risk factors, outcomes, and cost of hospital readmission after live related renal transplantation (LRRT). MethodsWe conducted a cross-sectional study and followed patients' re-admissions for six months whose LRRT was done in our center between September 2019 and June 2020. ResultsWe recruited 53 patients, 40 (75.5%) were male. The mean age was 36.9 ± 11.9 years. Donor gender was similar, and their mean age was 31.6 ± 9.2 years. The mean length of hospital stay after LRRT was 14 ± 2.2 days. A total of 81.1% were readmitted after LRRT within the first six months, with a total of 113 readmissions. The median time of readmission after LRRT was 66 days. The median readmission hospital stay was four days. The causes of readmission were surgical in 11 (9.7%), medical in 89 (78.8%), and combined medical and surgical in 13 (11.5%). Infection was the most common medical cause, followed by rejection. Statistically significant difference between readmission and non-readmission groups was found in estimated glomerular filtration rate (eGFR) at six month 61.3 ± 25.9 vs. 84.3 ± 36.1 mL/min/1.73 m 2 respectively (p = 0.02). The median cost of readmission was PKR 40629, equivalent to USD 261. ConclusionOver three-fourths of the patients were readmitted after LRRT within the first six months. The most common causes were infection and rejection. Readmissions after LRRT are associated with lower graft function at six months and a significant cost burden on the health system.

Incidence and Causes of Early Hospital Readmissions After Living-Donor Renal Transplant at King Abdulaziz Medical City, Riyadh

“…Regarding the association between sociodemographic factors and readmission after renal transplantation, the results suggest that there is no significant association between the gender, age, and BMI of the patients and their likelihood of readmission after renal transplantation. These findings are consistent with some previous studies, which also found no significant association between gender and readmission after renal transplantation [17]. It is because the factors that influence readmission rates are more related to medical complications and other individual patient characteristics rather than gender.…”

Effect of increasing age and ureteral stent implantation on urinary tract infections after kidney transplantation – update of recent literature

“…Infectious complications, especially UTIs are one of the most important causes for hospital readmission after transplantation. In this context, a recent research in 2022 has shed light on the considerable burden imposed by infectious complications as the leading cause of readmission after KTX with 49% of all cases, and with 39% of UTIs [ 18 ]. These complications not only contribute to the overall patient's well being but also pose an important cost burden on the healthcare system.…”