2018
DOI: 10.32474/oajom.2018.01.000111
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Re-Purposing Evodiamine as an Anti-Cancer Drug: Effects on Migration and Apoptosis

Abstract: Introduction: Evodiamine is a quinolone alkaloid compound obtained from a fruit described in traditional Chinese medicine. It has been in use for many centuries for the treatment of headaches, menstrual problems, abdominal pain and other ailments. In the western world, it is known as a controversial weight loss product and is sold over the counter as a nutritional supplement. Many freely sold weight loss products contain evodiamine associated with other supposed weight control chemicals. Even though there are … Show more

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Cited by 2 publications
(1 citation statement)
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References 115 publications
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“…On the other hand, cyanide has the capacity to decrease cellular energy, resulting in reduced growth of neoplastic cell resistance to perforations of the lysosomal membrane induced by ciprofloxacin. This is achieved by lowering the synthesis of the Hsp70 family of chaperone proteins [25,26].…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, cyanide has the capacity to decrease cellular energy, resulting in reduced growth of neoplastic cell resistance to perforations of the lysosomal membrane induced by ciprofloxacin. This is achieved by lowering the synthesis of the Hsp70 family of chaperone proteins [25,26].…”
Section: Discussionmentioning
confidence: 99%