Re-thinking treatment targets in child and adolescent psychiatry

Moreno, Carmen; Zuddas, Alessandro

doi:10.1007/s00787-019-01299-4

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…The better accuracy obtained by the CBCL in the ODD scale, where both instruments have 6 items, is probably due to the fact that in CABI, “angry/irritable mood” ( DSM -5) is calculated as a group apart, separated from the ODD, as they can also be part of depressive disorder, intermittent explosive disorder, and disruptive mood dysregulation disorder. The angry/irritable dimension is of primary importance in ODD (Moreno & Zuddas, 2019). Therefore, the separate location of this dimension is likely to have disadvantaged the results with the CABI.…”

Section: Discussionmentioning

confidence: 99%

Predictive validity for the clinical diagnosis of a new parent questionnaire, the CABI, compared with CBCL

Cianchetti

Faedda

Pasculli

et al. 2020

Clin Child Psychol Psychiatry

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Background: The questionnaires completed by the parents give a first general information on the behavioral problems of the child–adolescent, as a useful orientation to the clinical evaluation. The Child and Adolescent Behavior Inventory (CABI) is a 75-item parent questionnaire, which explores a large number of problem areas. The study of its predictive validity for the clinical diagnosis, in comparison with the Diagnostic and Statistical Manual of Mental Disorders ( DSM)-oriented scales of the Child Behavior Checklist (CBCL), can assess whether its use may be advantageous. Material and Methods: Parents/caregivers of 462 children and adolescents responded to both CABI and CBCL as a preliminary routine investigation. The results were compared with those of diagnoses obtained after the completion of the usual clinical procedure. Results: Accuracy values (probability of correct classification) resulted high for both instruments and significantly better for CABI anxiety and attention-deficit hyperactivity disorder (ADHD) scales, and for CBCL oppositional defiant disorder (ODD) and conduct disorder (CD) scales; no significant difference was found for depression scales. All the areas under the curve (AUC) of the receiver operating characteristic analysis reached excellent values, suggesting a very good predictive ability of the five scales of the two instruments. The comparison of AUC showed the CABI’s anxiety and ADHD scales to give significantly higher values than those of CBCL, indicating that these two scales have a better predictive ability. Conclusion: The study indicates a very good comparative (vs CBCL) and predictive validity of the CABI, suggesting an advantage in the use of this shorter questionnaire, available for free use both for clinical practice and supposedly for screening and epidemiological evaluations.

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Section: Discussionmentioning

confidence: 99%

Predictive validity for the clinical diagnosis of a new parent questionnaire, the CABI, compared with CBCL

Cianchetti

Faedda

Pasculli

et al. 2020

Clin Child Psychol Psychiatry

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“…According to this neuroscience-based classification, irritability is an excessive response of an individual faced with the impossibility to achieve an expected goal. As such, it has been linked to dysregulations of the autonomic nervous system [ 11 ] and the reward network. Another pathophysiological line of research conceptualizes irritability as an aberrant response to threat (e.g., irritable individuals may attack more rapidly and in broader contexts) [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Parent training for the treatment of irritability in children and adolescents: a multisite randomized controlled, 3-parallel-group, evaluator-blinded, superiority trial

Fongaro

Picot²,

Stringaris

et al. 2022

BMC Psychol

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Background Irritability is common in children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD), Oppositional Defiant Disorder (ODD) and with anxiety/depressive disorders. Although youth irritability is linked with psychiatric morbidity, little is known regarding its non-pharmacological treatments. Developing non-pharmacological treatments for children with severe, chronic irritability is an important target for clinical research. To achieve this goal, we will test the benefits of parent-focused therapies in reducing irritability. The aim of the study is to compare Parent Management Training (PMT) and Non-Violent Resistance Training (NVR) programs with treatment-as-usual (TAU) on the improvement of irritability in children and adolescents with a baseline Parent-rated Affective Reactivity Index of 4 or higher, in the context of ADHD and other emotional and behavioural disorders. Additionally, we will assess (i) improvement of irritability at different times and according to different informants (parents, children, clinicians); (ii) improvement of parental strategies; and (iii) acceptability of the interventions, exploring possible mechanisms of the therapeutic effect. Methods Two hundred and seventy participants between 6 and 15 years with ADHD and other emotional and behavioural disorders will be recruited and randomly assigned with their parents to the PMT, NVR, and TAU groups. PMT and NVR programs have 10 online sessions and two booster sessions at 1 and at 3 months. The primary outcome measure is the change from baseline at 3 months after completion of the program of the Clinician-rated Affective Rating Scale (CL-ARI) assessed by a blind evaluator. Secondary outcome measures include the change from baseline from those scales: the CL-ARI, the Clinical Global Impression Improvement scale, the Parenting and Familial Adjustment Scales, the Child-rated Cranky thermometers and the Parent-rated ARI. We will assess the parent’s expressed emotions and reflexivity during the online five-minute speech sample, clinical dimensions through the Child Behavior Checklist 6–18 and the Inventory of Callous Unemotional traits. Evaluations will be done remotely at baseline and at 1- and 3-months follow-up visits. Discussion We expect a benefit in controlling irritability in the treatment groups. This will constitute an important achievement in promoting parental support programs in the treatment of irritability in the context of emotional and behavioural disorders. Clinicaltrials.gov. Number: NCT05528926. Registered on the 2nd of September, 2022.

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Re-thinking treatment targets in child and adolescent psychiatry

Cited by 2 publications

References 16 publications

Predictive validity for the clinical diagnosis of a new parent questionnaire, the CABI, compared with CBCL

Predictive validity for the clinical diagnosis of a new parent questionnaire, the CABI, compared with CBCL

Parent training for the treatment of irritability in children and adolescents: a multisite randomized controlled, 3-parallel-group, evaluator-blinded, superiority trial

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