Reacciones capilares de las nuevas terapias diana dirigidas contra el cáncer

Background Mucocutaneous adverse events are common during anticancer treatment, with variable consequences for the patient and their therapeutic regimen. Objective To evaluate the most common adverse events, as well as the drugs associated with their appearance and the consequences for cancer treatment. Methods A retrospective study was carried out through the analysis of patients treated at the Clinical Dermatology Unit of a public oncologic hospital. Results A total of 138 patients with 200 adverse events were evaluated. The most commonly identified adverse events were nail and periungual changes (20%), papulopustular eruptions (13%), acneiform eruptions (12%), hand-foot syndrome (6.5%), hand-foot skin reaction (6%), and xerosis (6%). The most frequently associated antineoplastic treatment groups were classical chemotherapy (46.2%), target therapy (32.3%), and other non-antineoplastic drugs used in neoplasia protocols (16.5%). Of the total number of patients, 17.4% had their treatment suspended or changed due to a dermatological adverse event. Study limitations Retrospective study and analysis of patients who were referred for specialized dermatological examination only, not allowing the assessment of the actual incidence of adverse events. Conclusion A wide variety of dermatological manifestations are secondary to antineoplastic treatment with several different drugs resulting, not rarely, in the interruption or modification of therapeutic regimens.

show abstract

Eritema escrotal como manifestación inicial de toxicodermia por pazopanib

Benavent¹,

Díaz²,

Climent³

et al. 2021

Actas Dermo-Sifiliográficas

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Reacciones capilares de las nuevas terapias diana dirigidas contra el cáncer

Cited by 11 publications

References 88 publications

Diagnosis and Management of Dermatologic Adverse Events from Systemic Melanoma Therapies

Diagnosis and Management of Dermatologic Adverse Events from Systemic Melanoma Therapies

Cutaneous adverse events to systemic antineoplastic therapies: a retrospective study in a public oncologic hospital

Eritema escrotal como manifestación inicial de toxicodermia por pazopanib

Contact Info

Product

Resources

About