Reaction of 2‐[(2‐Oxo‐2‐arylethyl)anilino]‐1‐aryl‐1‐ethanones with o‐phenylenediamine: Formation of quinoxalines

Abstract

in Wiley InterScience (www.interscience.wiley.com).Unexpected quinoxalines (3) have been obtained from a one-pot reaction of 2-[(2-oxo-2-arylethyl)anilino]-1-aryl-1-ethanones (1) with o-phenylenediamine (2) in the presence of a catalytic amount of p-toluene sulfonic acid. The reaction presumably involves a tandem carbonyl addition-eliminative cyclization-air oxidation sequence.