Reaction of ?-aroylacrylic acids with 1-substituted 3,4-dihydroisoquinolines

Pyrrolo[2,1-a]isoquinolines (review)

“…Thus, the reaction of the enarnine (LXXXVI) with fumaric and maleic acids or their esters gives compounds (LXXXVII), and the reaction with cinnamic acid or its methyl ester gives the laetams (LXXXVIII) [159]. For example, the reaction with methyl B-benzoylacrylate leads to compound (LXXXIX) [161]. For example, the reaction with methyl B-benzoylacrylate leads to compound (LXXXIX) [161].…”