“…In the case of alcohol and other substance use disorders, studies have suggested that longer duration of alcohol use disorder (AUD), methamphetamine use disorder, and heroin use are correlated with more cognitive deficits. This is particularly true for response inhibition, reaction time, and cognitive flexibility (Laloyaux et al., 2012; Martinovic-Mitrovic et al., 2008; Monterosso, Aron, Cordova, Xu, & London, 2005). Moreover, research in AUD suggested that early onset of problems with alcohol is associated with stronger genetic susceptibility and poorer treatment outcome (Babor et al., 1992; Carpenter & Hasin, 2001; Cloninger, 1987; Schuckit et al., 1995).…”