Reactions Catalyzed by Anion Exchange Resins Knoevenagel Condensation

Astle, Melvin J.; Zaslowsky, J. A.

doi:10.1021/ie50516a031

Cited by 37 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Since then, polymers with functional sites as solid supports in heterogeneous catalysis, for example in mixed‐bed reactors, have been used widely 3–5. This approach goes back to the ground‐breaking work by Astle and Zaslowsky6 and Manecke and Storck7 on polymeric reagents. In recent investigations of sol–gel processes with encapsulated opposing reagents by Gelman et al8 the concept of “wolf‐and‐lamb” reactions has been rediscovered and has emerged as a powerful tool to probe “site‐isolation” effects in cross‐linked solid materials.…”

Section: Methodsmentioning

confidence: 99%

Sequential One‐Pot Reactions Using the Concept of “Site Isolation”

Voit

2006

Angew Chem Int Ed

120

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Sequential One‐Pot Reactions Using the Concept of “Site Isolation”

Voit

2006

Angew Chem Int Ed

120

View full text Add to dashboard Cite

show abstract

“…The wider use of SPOS has enormous potential, illustrated perhaps most dramatically by the orchestrated multistep SPS approach so elegantly reduced to practice by Ley's group 46. Early examples of the consecutive and sometimes concurrent use of different supported species have been reported,89–92 and the British Petroleum Etherol process93 (Fig. 10) for the production of branched ethers from a mixed C 4 stream is a marvelous large‐scale industrial example.…”

Section: Convergence Of Solid‐phase Activitiesmentioning

confidence: 99%

Polymer‐supported reagents, catalysts, and sorbents: Evolution and exploitation—A personalized view

Sherrington

2001

J. Polym. Sci. A Polym. Chem.

102

View full text Add to dashboard Cite

ABSTRACT:The solid-phase method for oligopeptide synthesis was introduced by Professor Bruce Merrifield in 1963, but in practice the origins of polymer-supported reagents, catalysts, and so forth trace back to the early development of ion exchange and catalysis by sulfonic acid resins. This highlight summarizes how the evolution of solid-phase organic synthesis occurred in parallel with the development of supported reactive species and indicates the interchange between these areas in the last 30 years or so. The treatment is essentially a personalized one as seen from the author's own laboratory in the United Kingdom and is not intended to review the whole field. The emergence of the international series of conferences on polymer-supported organic chemistry is emphasized as a key development that stimulated and maintained the area before its importance was recognized more widely by both academic and industrial chemists. The requirement of robotic technologies, as the basis for high-throughput combinatorial and parallel synthesis in the pharmaceutical industry, has brought the relevance of supported chemistry to the attention of all synthetic chemists. At the same time, the recognition that all industrial chemical processes need to meet appropriate environmental standards has focused attention on the use of heterogenized reactive species as a potentially important technology for achieving the greening of chemistry. These two factors have brought polymer-supported reactive chemistry to center stage, so to speak, and the early principles laid down over 2 decades ago are now being developed and exploited at an amazing rate. From a rather slow start, through a number of ups and downs in its development, the area of polymer-supported chemistry now seems poised to join the more routine world of synthesis and to become a methodology used by all as and when appropriate.

show abstract

“…B. in Mischbett‐Reaktoren 3–5. Dieser Ansatz stützt sich auch auf die bahnbrechenden Arbeiten von Astle und Zaslowsky6 sowie Manecke und Storck7 zu Polymerreagentien. Neuere Arbeiten zu Sol‐Gel‐Prozessen mit eingeschlossenen orthogonalen Reagentien von Gelman et al8 haben gezeigt, dass man mithilfe von “Wolf‐and‐Lamb”‐Reaktionen ermitteln kann, wie effizient die reaktiven Zentren in einer Festphase voneinander getrennt sind (“site isolation”).…”

Section: Methodsunclassified

Sequenzielle Eintopfreaktionen mithilfe isolierter aktiver Zentren

Voit

2006

Angewandte Chemie

View full text Add to dashboard Cite

Saure und basische aktive Zentren können getrennt werden, indem man sie in den Kernen von Sternpolymeren einschließt (siehe Bild). Fréchet, Hawker und Mitarbeiter nutzten derartige Polymerkatalysator‐Paare kürzlich für Mehrstufen‐Eintopfreaktionen in homogener Phase. Auf einem ähnlichen Konzept gründet ein System von Kaneda et al. mit unterschiedlichen Ton‐Schichtstrukturen als Heterogenkatalysatoren.

show abstract

Reactions Catalyzed by Anion Exchange Resins Knoevenagel Condensation

Cited by 37 publications

References 0 publications

Sequential One‐Pot Reactions Using the Concept of “Site Isolation”

Sequential One‐Pot Reactions Using the Concept of “Site Isolation”

Polymer‐supported reagents, catalysts, and sorbents: Evolution and exploitation—A personalized view

Sequenzielle Eintopfreaktionen mithilfe isolierter aktiver Zentren

Contact Info

Product

Resources

About