Reactions of 6-methoxy-1,2,3,4-tetrahydro-?-carbolin-1-ones and their dichlorophosphoryl-substituted derivatives with acetic anhydride

Pd/Cu Cocatalyzed Oxidative Tandem C–H Aminocarbonylation and Dehydrogenation of Tryptamines: Synthesis of Carbolinones

“…Alosetron, a tetrahydro-γ-carbolinone, is an FDA-approved drug molecule treating women with severe diarrhea-predominant irritable bowel syndrome. In addition, carbolinones are versatile intermediates for the synthesis of indole-containing natural products . Therefore, chemists have devoted great efforts to the development of efficient methods toward these structures.…”