A catalytic enantioselective protocol for the synthesis of aryl−methyl organophosphorus compounds is reported. Utilizing a chiral phosphoric acid as a catalyst, a wide range of indole derivatives reacted with phosphorylated quinomethanes in high yield with excellent enantioselectivity. This is the first report on the application of phosphorylated quinomethanes in asymmetric synthesis.
A catalytic enantioselective protocol for the synthesis of aryl−methyl organophosphorus compounds is reported. Utilizing a chiral phosphoric acid as a catalyst, a wide range of indole derivatives reacted with phosphorylated quinomethanes in high yield with excellent enantioselectivity. This is the first report on the application of phosphorylated quinomethanes in asymmetric synthesis.
A FUNDAMENTAL QUEST FOR ALKYL RADICAL GENERATION UNDER MILD CONDITIONS THROUGH PHOTOINDUCED BRØNSTED ACID CATALYSIS IS ADDRESSED. THE OPTIMIZED PROTOCOL DOES NOT REQUIRE ANY ORGANIC DYES OR TRANSITION METAL PHOTOCATALYST....
A visible light induced cycloaddition of 1,3-dienes and p-quinonemethides through EDA complexation is reported. The reaction does not require any external photocatalyst, oxidant or additive. Generality of the method is...
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