Reactions of β‐Methoxyvinyl Trifluoromethyl Ketones with 2‐Pyridinecarboxamidrazone. A Convenient Route to Trifluoromethylated 4,5‐Dihydro‐1H‐1‐picolinoylpyrazole Hydrochlorides.

Abstract

Pyrazole derivatives Pyrazole derivatives R 0180Reactions of β-Methoxyvinyl Trifluoromethyl Ketones with 2-Pyridinecarboxamidrazone. A Convenient Route to Trifluoromethylated 4,5-Dihydro-1H-1-picolinoylpyrazole Hydrochlorides. -A convenient route to trifluoromethylated pyrazole hydrochlorides of type (III) is described. The structure of (IIIb) is confirmed by X-ray structure analysis. -(BONACORSO*, H. G.; LEWANDOWSKI, H.; DREKENER, R. L.; COSTA, M. B.; PEREIRA, C. M. P.; WASTOWSKI, A. D.; PEPPE, C.; MARTINS, M. A. P.; ZANATTA, N.; J. Fluorine Chem. 122 (2003) 2, 159-163; Dep. Quim., Univ. Fed. Santa Maria, 97105 Santa Maria, Brazil; Eng.) -M. Bohle 48-118