Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection

González, Mónica Pérez; Rios, Radames; Pappaterra, Mariella; Hernández, Miguel Díaz; Toledo, Allison; Emanuelli, Andrés; Kurup, Shree K.; Oliver, Armando L.

doi:10.1155/2021/7336488

Cited by 15 publications

(18 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…PCR from the aqueous humor sample was positive for both HSV and VZV. Of note, 4 cases of ARN (3 cases were HSV related, 1 case was VZV related) have been reported after the infection of SARS-CoV-2 (22)(23)(24). The unconceivable risk of aberrant immune reactions leading to the reactivation of HSV or VZV needs to be kept in mind after the COVID-19 vaccination.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Associated Ocular Adverse Reactions With Inactivated COVID-19 Vaccine in China

et al. 2022

View full text Add to dashboard Cite

The vaccine is still the best clinical measure for effective prevention and control of coronavirus disease 2019 (COVID-19). The vaccine-associated ocular adverse reactions should be noted in detail among the medical community. We reported twelve eyes of 9 patients presented at the Department of Ophthalmology, Qilu Hospital of Shandong University from March to August 2021 with ocular complaints following COVID-19 vaccination. The main inclusion criterion was the development of ocular symptoms within 14 days after receiving a dose of an inactivated COVID-19 vaccine. The mean (SD) age was 44.7 ± 16.5 years (range, 19–78 years), among which seven (77.8%) cases were women. The mean time of ocular adverse events was 7.1 days (range, 1–14 days) after receiving the inactivated COVID-19 vaccine. One patient was diagnosed with choroiditis, 1 with uveitis, 4 with keratitis, 1 with scleritis, 1 with acute retinal necrosis, and 1 with iridocyclitis. Although the causal relationship between vaccines and ocular adverse events cannot be established from this case series report, physicians should pay attention to the ocular adverse reactions following the COVID-19 vaccine administration.

show abstract

Section: Discussionmentioning

confidence: 99%

Case Report: Associated Ocular Adverse Reactions With Inactivated COVID-19 Vaccine in China

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Interestingly, during the COVID-19 pandemic, besides reports of neuroretinitis after SARS-CoV-2, there were also reports of reactivation of acute retinal necrosis due to HSV after COVID-19 in few cases [ 45 , 46 ].…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Encephalitis and Neuroretinitis After COVID-19 in a Young Adult: A Case Report

Poursadeghfard

Dorche

Nemati³

et al. 2021

J Neurol Res

View full text Add to dashboard Cite

Coronavirus disease 2019 (COVID-19) pandemic greatly impacted many aspects of life in the world. Both neurological and ophthalmologic presentations after COVID-19 have been reported. Herein, we present a case of both neuroretinitis and encephalitis after COVID-19 in a young adult. Both presentations are among the rare presentations of COVID-19. Similar manifestations were not reported previously. The 18-year-old previously healthy girl initially presented with low-grade fever, nausea, vomiting, body pain, and headache. The patient tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcriptase-polymerase chain reaction (PCR) by using a nasal swab. Two days after the onset of COVID-19 symptoms, she reported blurred vision in both eyes, progressing to only light perception in 3 days. Based on the ophthalmological evaluation, she was diagnosed with neuroretinitis. A few days later, she gradually became drowsy, so she was referred for neurological evaluation. Brain magnetic resonance imaging (MRI) showed bilateral medial temporal T2 and fluid-attenuated inversion recovery (FLAIR) hyper-signal lesions suggestive of encephalitis. A low-dose steroid was started to treat the neuroretinitis. After about 2 weeks, significant improvement in visual acuity and resolution of retinitis patches were observed. Our case is rare in respect of both neurological and ophthalmic involvement.

show abstract

“…Additionally, a PCR analysis of the right vitreous was positive for HSV-2, and the RT-PCR was positive for SARS-CoV-2 RNA. Thus, it was suggested that the SARS-CoV-2 infection might cause the reactivation of a latent HSV infection, with its contralateral involvement in patients who have a prior history of HSV-related acute retinal necrosis [ 51 ].…”

Section: Posterior Segment Of the Eyementioning

confidence: 99%

How Does SARS-CoV-2 Affect Our Eyes—What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?

Baj

Forma

Teresińska

et al. 2022

JCM

View full text Add to dashboard Cite

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has become a worldwide threat resulting in a pandemic in 2020. SARS-CoV-2 infection manifests itself as coronavirus disease 2019 (COVID-19) that is evidenced in a vast number of either specific or nonspecific symptoms. Except for typical (but nonspecific) symptoms such as fever, dry cough, or muscle weakness, the infected patients might also present atypical symptoms including neurological, dermatological, or ophthalmic manifestations. This paper summarizes the current state of knowledge regarding the onset, progression, and types of ophthalmic symptoms induced by SARS-CoV-2 infection recognized amongst the infected patients.

show abstract

Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection

Cited by 15 publications

References 19 publications

Case Report: Associated Ocular Adverse Reactions With Inactivated COVID-19 Vaccine in China

Case Report: Associated Ocular Adverse Reactions With Inactivated COVID-19 Vaccine in China

Simultaneous Encephalitis and Neuroretinitis After COVID-19 in a Young Adult: A Case Report

How Does SARS-CoV-2 Affect Our Eyes—What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?

Contact Info

Product

Resources

About