Reactive Arthritis: A Review

Kim, Paul S.; Klausmeier, Thomas; Orr, Donald P.

doi:10.1016/j.jadohealth.2008.12.007

Cited by 53 publications

(53 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In vivo, such infections elicit a strong inflammatory response, though that response is often more clinically apparent in men than in women, at least for urogenital infections (e.g. [7 ]). …”

Section: Chlamydial Biology: Increased Understanding Of Infection Pementioning

confidence: 99%

The pathogenic role of Chlamydia in spondyloarthritis

Gérard

Whittum-Hudson

Carter

et al. 2010

Current Opinion in Rheumatology

View full text Add to dashboard Cite

show abstract

Section: Chlamydial Biology: Increased Understanding Of Infection Pementioning

confidence: 99%

The pathogenic role of Chlamydia in spondyloarthritis

Gérard

Whittum-Hudson

Carter

et al. 2010

Current Opinion in Rheumatology

View full text Add to dashboard Cite

show abstract

“…13,16 Except for the symptoms enumerated in the diagnostic criteria, cutaneous and mucosal lesions are very characteristic for reactive arthritis. Circinate balanitis or vulvitis (balanitis circinata) is a frequent symptom coexisting with ReA 2,7,9,17 ; it occurs in 14%-40% of patients. 11 The lesions have a form of papules, transforming into annular or semicircular erythematous erosions with visible grayish white ridges.…”

Section: Resultsmentioning

confidence: 99%

“…4 The psoriasis-like lesions can occur in about 10%-20% of patients, usually in the area of the joints involved, on the scalp and in the navel area. 7,9 Additionally, the nail plates may be involved in the form of subungual hyperkeratosis in 6%-12% of patients. 10 In 15% ReA patients, with Yersinia infection, lesions in the form of erythema nodosum can be observed.…”

Section: Resultsmentioning

confidence: 99%

Cutaneous manifestation of reactive arthritis: Case report

Krajewska–Włodarczyk

Owczarczyk‐Saczonek

Placek

2015

Polish Annals of Medicine

View full text Add to dashboard Cite

Available online xxxKeywords: Reactive arthritisReiter disease Keratoderma blenorrhagicum Balanitis circinata a b s t r a c t Introduction: Reactive arthritis (ReA) is one of the forms of seronegative spondyloarthropathies.The difficulties in the diagnosis of reactive arthritis, despite a complex clinical picture, result from the lack of unequivocal diagnostic criteria, especially in the initial period. Diverse clinical manifestation of ReA may require the cooperation of many specialists.Aim: The case of a 59-year-old man with reactive arthritis caused by an acute Yersinia enterocolitica infection 3 weeks before was described.Case study: A 59-year-old patient, so far healthy, was admitted due to fever for a few days, pain and swelling of crurotalar joints, pain in the left part of the lumbosacral region, escalating at night, and additional complaints impeding urinating. Joint involvement was accompanied by numerous cutaneous and mucosal lesions.Results and discussion: In this case the presence of characteristic cutaneous symptoms as keratoderma blenorrhagicum and balanitis circinata allowed to identify the disease quickly, despite a short course of the disease. The presence of antibodies of Y. enterocolitica IgA was noticed, without the presence of IgG and IgM. The presence of HLA B27 antigen was positive.In this case, the occurrence of many characteristic cutaneous lesions enabled a quick identification of the disease, despite the difficulties with determining the etiological factor. Conclusions:The diagnosis of ReA is clinical, based on the history and physical examination findings. A high index of suspicion is required because no laboratory tests, markers or imaging finding allow diagnosing of ReA. The most important is proper cooperation between a rheumatologist and a dermatologist.# 2015 Warmińsko-Mazurska Izba Lekarska w Olsztynie. Published by Elsevier Sp. z o.o.All rights reserved.

show abstract

“…The role of infection for chronic arthritis is still not clear. Components of triggering bacteria including nucleic acids and proteins have been identified in the synovium and in circulatory monocytes of patients with rheumatoid arthritis (25). Clinically, the duration of reactive arthritis for more than 6 months is already the sign of development of chronicity (31).…”

Section: Discussionmentioning

confidence: 99%

Proinflammatory S100 proteins as clinical markers of juvenile idiopathic arthritis

Rusoniene¹,

Panavienė²,

Eidukaitė³

et al. 2014

AML

View full text Add to dashboard Cite

Objectives. Proteins of the S100 family (S100A8/9, or calprotectin) are known to be useful diasease activity biomarkers of JIA. We hypothesize that titres calprotectin in serum and synovial fluid of children with acute and unconfirmed inflammatory joint symptoms will identify patients who will progress to JIA and our aim is to examine its prognostic value.Methods. A standardized diagnostic evaluation and analysis of serum S100A8/A9 was performed in 115 children with acute (symptoms up to 6 weeks) arthritis as well as in 59 healthy individuals. 47 arthritis patients underwent joint fluid aspiration and samples were collected at the time of presentation. Proteins in serum and synovial fluid were measured by ELISA and compared by the unpaired t test. Arthritis outcome (chronic or transient arthritis) was recorded at 1-and 2-year follow-up periods. JIA diagnosis, disease activity and remission were established according to ILAR and ACR recommendations.Results. The levels of serum and synovial fluid S100A8/A9 were significantly higher in patients with arthritis compared to the levels in healthy individuals (p < 0.0001). Serum calprotectin correlated well with disease activity (r = 0.539, p < 0.05) and the level in synovial fluid (r = 0.598, p < 0.001). A binary logistic regression model showed that high level of calprotectin predicted chronic arthritis development together with the presence of morning stiffness and higher swollen joint count at the baseline (p < 0.001).Conclusions. We have demonstrated that high levels of baseline serum S100A8/A9 (calprotectin) have a prognostic value in predicting a group of patients who following the onset of arthritis will have a chronic disease from those with transient and self-limiting disease.

show abstract

Reactive Arthritis: A Review

Cited by 53 publications

References 33 publications

The pathogenic role of Chlamydia in spondyloarthritis

The pathogenic role of Chlamydia in spondyloarthritis

Cutaneous manifestation of reactive arthritis: Case report

Proinflammatory S100 proteins as clinical markers of juvenile idiopathic arthritis

Contact Info

Product

Resources

About