Reactive Arthritis: Treatment Challenges and Future Perspectives

Wendling, Daniel; Prati, Clément; Chouk, Mickaël; Verhoeven, Frank

doi:10.1007/s11926-020-00904-9

Cited by 33 publications

(34 citation statements)

References 44 publications

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“…Molecular mimicry appears to play a major role in the pathogenesis [ 7 ]. Although viral infections are known to potentially induce reactive arthritis [ 41 ], viremia was documented in only 15% of cases of COVID-19 [ 42 ]. Interleukin 17 A has been involved in the pathogenesis of both reactive arthritis and spondyloarthritis in general [ 41 ] and also in the hyper inflammatory state of COVID-19 [ 43 ].…”

Section: Resultsmentioning

confidence: 99%

Rheumatological complications of Covid 19

Zacharias

Dubey

Koduri

et al. 2021

Autoimmunity Reviews

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Introduction COVID-19 has caused unprecedented hardships in the 21st century with more than 150 million infections. Various immunological phenomena have been described during the course of the infection, and this infection has also triggered autoimmunity. Rheumatological illnesses have been described following resolution of the acute infection; hence we sought to conduct a review of the rheumatological complications of COVID-19. Methods We conducted a literature search for articles relating to sequelae of COVID-19 from Jan 2020 to 30th April 2021. Results We found a number of reports of inflammatory arthritis after SARS-CoV-2 infection. SLE and renal disease have been described, and vasculitis also appears to be a common complication. Rhabdomyolysis and myositis has also been reported in a number of patients. We also found some evidence of large vessel vasculitis in ‘long COVID’ patients. Conclusions This review highlights a number of important complications such as inflammatory arthritis, lupus-like disease, myostis and vasculitis following SARS-CoV-2 infection.

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Section: Resultsmentioning

confidence: 99%

Rheumatological complications of Covid 19

Zacharias

Dubey

Koduri

et al. 2021

Autoimmunity Reviews

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“…Individuals with the HLA-B27 allele or with a family history of spondyloarthritis apparently have an increased risk of developing reactive arthritis. 2 Since the emergence of COVID-19, only a few cases of post-COVID-19 reactive arthritis have been published. [6][7][8][9] There seems to be some common traits in these case reports.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis is based on a clinical assessment following the exclusion of other differential diagnoses. 2 Swollen inflamed joints are also seen in septic arthritis, but this condition most often presents as monarthritis. 3 Before giving antibiotic therapy, we aspirated synovial joint fluid.…”

Section: Differential Diagnosismentioning

confidence: 99%

Reactive arthritis after COVID-19

2021

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A previously healthy 53-year-old man was hospitalised for 12 days due to COVID-19 with shortness of breath. A few days after discharge from hospital, the patient developed fever and severe pain in several joints in the lower extremities. The pain was so severe that the patient was unable to stand on his feet. Synovial fluid from the right-side knee contained a high number of polynuclear cells and a few mononuclear cells. Microscopy, culture and PCR tests for bacterial infection were all negative. Furthermore, the patient tested negative for rheumatoid factor, anti-cyclic citrullinated peptide and human leukocyte antigen (HLA)-B27. Thus, the condition was compatible with reactive arthritis. The condition improved markedly after a few days’ treatment with non-steroid anti-inflammatory drugs and prednisolone.

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“…The use of biological agents (anti-TNF-α) is given as soon as possible if there are indications or after refractory conditions using a conventional DMARD. 24,25 • NSAIDs can be given short term (≤15 days)…”

Section: Endoscopy and Colonoscopymentioning

confidence: 99%

Indonesian Rheumatologist Association (IRA) Recommendations for Diagnosis and Management of Peripheral Spondyloarthritis 2021

et al. 2021

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Objective. Spondyloarthritis recommendations are made to provide guidance in diagnosis, treatment, and monitoring of peripheral spondyloarthritis cases.Method. Literature searches were conducted online. The drafting team determines the levels of evidence (LOE) and grades of recommendation (GOR). After conducting a discussion, each recommendation that has been agreed upon by the drafting team is then classified based on the levels of evidence and grades of recommendation. The final step in the preparation of these recommendations is to determine the level of agreement (LOA) on each recommendation carried out by a team of panelists who have been appointed by IRA.Result. Thirty five recommendations regarding peripheral spondyloarthritis were compiled. There are 6 strong recommendation or GOR A for psoriatic arthritis and 8 recommendations for enteropathic arthritis.Conclusion. These recommendations provide directions for clinicians to diagnose and to manage peripheral spondyloarthritis.

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Reactive Arthritis: Treatment Challenges and Future Perspectives

Cited by 33 publications

References 44 publications

Rheumatological complications of Covid 19

Rheumatological complications of Covid 19

Reactive arthritis after COVID-19

Indonesian Rheumatologist Association (IRA) Recommendations for Diagnosis and Management of Peripheral Spondyloarthritis 2021

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