Reactive hyperplasic lesions of the oral cavity: A survey of 295 cases at a Tertiary Health Institution in Kerala

Abstract

Background:The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at a Tertiary Health Institution in Kerala and compare these data with those of previously reported studies.Materials and Methods:The patient case files from the Department of Oral and Maxillofacial Pathology during the period between January 2007 and December 2011 were reviewed for cases of RHLs of the oral cavity. Both clinical and histopathological diagnoses of reactive lesions were selected for the study. Data including the type of the lesion, age, gender and the site involved were collected.Results:From a total of 2753 cases reviewed, 295 histologically diagnosed cases of RHLs were obtained with a prevalence of 10.7%. The data consist of 85 (28.8%) males and 210 (71.2%) females. The most common lesion clinically was traumatic fibroma (69.3%) and histologically fibrous hyperplasia (51.9%). The reactive lesions clinically presented as either sessile (54.9%) or pedunculated (45.1%) lesions.Conclusion:The clinical features of reactive hyperplasia among our patients were similar to those reported previously with divergence in some analyzed data. The novelty in our study was the correlation between histopathology and clinical features which were not reported in literature until date.

Reactive lesions of oral cavity: A retrospective study of 659 cases

“…IFH comprised 47.64% of cases in the present study, and similar finding has been recorded by Jaffrey. [ 1 ] Histologically, IFH consists of predominantly inflammatory cell infiltration, vascular engorgement, and edema. [ 6 ]…”

“…Reactive lesions (RLs) are clinicopathologically benign, reactive, solitary, swelling occurring due to chronic and recurrent tissue injury leading to extreme or exuberant tissue response. [ 1 2 ] They are commonly evident in gingiva, and sometimes, other sites are involved. RLs are typically developed in response to chronic inflammation caused by various forms of low-grade chronic irritations to the oral mucosa.…”

Oral Adenosquamous Carcinoma Mimicking a Pyogenic Granuloma: A Challenging Diagnosis

“…Some pedunculated lesions were not included in clinical diagnostic hypothesis, as fibroma and hyperplasia (12), because of the fast-growing enlargement of the nodule. Neural tumors also occur on the palate, and only in rare occasions can be pedunculated, as solitary neurofibroma (13).…”

Avaliação da alteração da polaridade das células basais epiteliais em hiperplasias fibrosas inflamatórias

“…As hiperplasias fibrosas inflamatórias (HFI) são aumentos nodulares não neoplásicos que se desenvolvem em resposta à lesão tecidual crónica e recorrente, e sua atividade proliferativa pode ser iniciada por irritantes locais. 1 As displasias epiteliais caracterizam -se por alterações tanto celulares quanto arquiteturais do epitélio presente na mucosa oral. 2 Quando avaliado histologicamente, essas alterações têm início na camada basal e parabasal do epitélio, avançando de acordo com o estágio da displasia para seu restante.…”