Reactive Oxygen Species Production Mediated by Humic-like Substances in Atmospheric Aerosols: Enhancement Effects by Pyridine, Imidazole, and Their Derivatives

Dou, Jing; Lin, Peng; Kuang, Binyu; Yu, Jian

doi:10.1021/es5059378

Cited by 143 publications

(123 citation statements)

References 43 publications

Supporting

Mentioning

117

Contrasting

Order By: Relevance

“…S9). Dou et al (2015) showed that by forming H-bonds with hydroquinones, imidazole derivatives are capable of facilitating electron transfer from hydroquinones to molecular oxygen, accelerating the redox cycling of quinones and enhancing the oxidation of DTT (Scheme S4). In the DTT enhancement test, a 250 µL 2,4-dimethylimidazole aqueous solution (5 mM) was mixed with a 450 µL SOA PILS sample to get a 700 µL mixture.…”

Section: Pan Analysismentioning

confidence: 99%

“…The amount of PAN was measured using the Griess assay and that of organic hydroperoxides was measured using the 4-nitrophenylboronic acid (NPBA) assay. The contribution of quinones to the oxidative potential of SOA was estimated by the enhancement of DTT consumption in the presence of 2,4-dimethylimidazole, a co-catalyst for the redox cycling of quinones (Dou et al, 2015). In addition to particulate oxidizers, the contribution of electron-deficient alkenes to DTT activity was investigated for aromatic SOA (toluene SOA).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NOx levels

Jiang

Jang

2017

Atmos. Chem. Phys.

View full text Add to dashboard Cite

Abstract. When hydrocarbons (HCs) are atmospherically oxidized, they form particulate oxidizers, including quinones, organic hydroperoxides, and peroxyacyl nitrates (PANs). These particulate oxidizers can modify cellular materials (e.g., proteins and enzymes) and adversely modulate cell functions. In this study, the contribution of particulate oxidizers in secondary organic aerosols (SOAs) to the oxidative potential was investigated. SOAs were generated from the photooxidation of toluene, 1,3,5-trimethylbenzene, isoprene, and α-pinene under varied NO x levels. Oxidative potential was determined from the typical mass-normalized consumption rate (reaction time t = 30 min) of dithiothreitol (DTT t ), a surrogate for biological reducing agents. Under high-NO x conditions, the DTT t of toluene SOA was 2-5 times higher than that of the other types of SOA. Isoprene DTT t significantly decreased with increasing NO x (up to 69 % reduction by changing the HC / NO x ratio from 30 to 5). The DTT t of 1,3,5-trimethylbenzene and α-pinene SOA was insensitive to NO x under the experimental conditions of this study. The significance of quinones to the oxidative potential of SOA was tested through the enhancement of DTT consumption in the presence of 2,4-dimethylimidazole, a co-catalyst for the redox cycling of quinones; however, no significant effect of 2,4-dimethylimidazole on modulation of DTT consumption was observed for all SOA, suggesting that a negligible amount of quinones was present in the SOA of this study. For toluene and isoprene, massnormalized DTT consumption (DTT m ) was determined over an extended period of reaction time (t = 2 h) to quantify their maximum capacity to consume DTT. The total quantities of PANs and organic hydroperoxides in toluene SOA and isoprene SOA were also measured using the Griess assay and the 4-nitrophenylboronic acid assay, respectively. Under the NO x conditions (HC / NO x ratio: 5-36 ppbC ppb −1 ) applied in this study, the amount of organic hydroperoxides was substantial, while PANs were found to be insignificant for both SOAs. Isoprene DTT m was almost exclusively attributable to organic hydroperoxides, while toluene DTT m was partially attributable to organic hydroperoxides. The DTT assay results of the model compound study suggested that electrondeficient alkenes, which are abundant in toluene SOA, could also modulate DTT m .

show abstract

Section: Pan Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NOx levels

Jiang

Jang

2017

Atmos. Chem. Phys.

View full text Add to dashboard Cite

show abstract

“…At the global scale, the most recent estimates for the year 2000 (Lamarque et al, 2010) have shown that anthropogenic combustions and biomass burning roughly generate about 65 and 35 % of EC emissions, respectively, and 35 and 65 % of primary OC emissions. OC and EC not only contribute to the overall PM 2.5 load, but these components also have specific public health concerns because of their interactions with the human body (Dou et al, 2015;Shi et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Mass concentration, optical depth and carbon composition of particulate matter in the major southern West African cities of Cotonou (Benin) and Abidjan (Côte d'Ivoire)

Djossou

Léon²,

Akpo

et al. 2018

Atmos. Chem. Phys.

View full text Add to dashboard Cite

Abstract. Air quality degradation is a major issue in the large conurbations on the shore of the Gulf of Guinea. We present for the first time PM 2.5 time series collected in Cotonou, Benin, and Abidjan, Côte d'Ivoire, from February 2015 to March 2017. Measurements were performed in the vicinity of major combustion aerosol sources: Cotonou/traffic (CT), Abidjan/traffic (AT), Abidjan/landfill (AL) and Abidjan/domestic fires (ADF). We report the weekly PM 2.5 mass and carbonaceous content as elemental (EC) and organic (OC) carbon concentrations. We also measure the aerosol optical depth (AOD) and the Ångström exponent in both cities. The average PM 2.5 mass concentrations were 32 ± 32, 32 ± 24 and 28 ± 19 µg m −3 at traffic sites CT and AT and landfill site AL, respectively. The domestic fire site shows a concentration of 145 ± 69 µg m −3 due to the contribution of smoking and roasting activities. The highest OC and EC concentrations were also measured at ADF at 71 ± 29 and 15 ± 9 µg m −3 , respectively, while the other sites present OC concentration between 8 and 12 µg m −3 and EC concentrations between 2 and 7 µg m −3 . The OC / EC ratio is 4.3 at CT and 2.0 at AT. This difference highlights the influence of two-wheel vehicles using gasoline in Cotonou compared to that of four-wheel vehicles using diesel fuel in Abidjan. AOD was rather similar in both cities, with a mean value of 0.58 in Cotonou and of 0.68 in Abidjan. The seasonal cycle is dominated by the large increase in surface mass concentration and AOD during the long dry season (December-February) as expected due to mineral dust advection and biomass burning activities. The lowest concentrations are observed during the short dry season (August-September) due to an increase in surface wind speed leading to a better ventilation. On the other hand, the high PM 2.5 / AOD ratio in the short wet season (October-November) indicates the stagnation of local pollution.

show abstract

“…Oxidative stress is mediated by reactive oxygen species (ROS), including OH, H 2 O 2 and superoxide (O − 2 ), as well as organic radicals (Pryor et al, 1995;Winterbourn, 2008;Birben et al, 2012;. Upon PM deposition into the respiratory tract and interactions with lung antioxidants, H 2 O 2 can be generated by redox-active components contained in PM 2.5 such as transition metals (Charrier et al, 2014;Fang et al, 2016), semiquinones (Kumagai et al, 1997;Cho et al, 2005;McWhinney et al, 2013) and humic-like substances (Kumagai et al, 1997;Cho et al, 2005;Lin and Yu, 2011;Charrier et al, 2014;Dou et al, 2015;Fang et al, 2016;Verma et al, 2015a). H 2 O 2 can be converted into highly reactive OH radicals via Fenton-like reactions with iron and copper ions (Charrier et al, 2014;Enami et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Quantification of environmentally persistent free radicals and reactive oxygen species in atmospheric aerosol particles

et al. 2016

View full text Add to dashboard Cite

Abstract. Fine particulate matter plays a central role in the adverse health effects of air pollution. Inhalation and deposition of aerosol particles in the respiratory tract can lead to the release of reactive oxygen species (ROS), which may cause oxidative stress. In this study, we have detected and quantified a wide range of particle-associated radicals using electron paramagnetic resonance (EPR) spectroscopy. Ambient particle samples were collected using a cascade impactor at a semi-urban site in central Europe, Mainz, Germany, in May-June 2015. Concentrations of environmentally persistent free radicals (EPFR), most likely semiquinone radicals, were found to be in the range of (1-7) × 10 11 spins µg −1 for particles in the accumulation mode, whereas coarse particles with a diameter larger than 1 µm did not contain substantial amounts of EPFR. Using a spin trapping technique followed by deconvolution of EPR spectra, we have also characterized and quantified ROS, including OH, superoxide (O − 2 ) and carbon-and oxygen-centered organic radicals, which were formed upon extraction of the particle samples in water. Total ROS amounts of (0.1-3) ×10 11 spins µg −1 were released by submicron particle samples and the relative contributions of OH, O − 2 , C-centered and O-centered organic radicals were ∼ 11-31, ∼ 2-8, ∼ 41-72 and ∼ 0-25 %, respectively, depending on particle sizes. OH was the dominant species for coarse particles. Based on comparisons of the EPR spectra of ambient particulate matter with those of mixtures of organic hydroperoxides, quinones and iron ions followed by chemical analysis using liquid chromatography mass spectrometry (LC-MS), we suggest that the particle-associated ROS were formed by decomposition of organic hydroperoxides interacting with transition metal ions and quinones contained in atmospheric humic-like substances (HULIS).

show abstract

Reactive Oxygen Species Production Mediated by Humic-like Substances in Atmospheric Aerosols: Enhancement Effects by Pyridine, Imidazole, and Their Derivatives

Abstract: 13Ambient particulate matter (PM) can cause adverse health effects via their ability to produce

Cited by 143 publications

References 43 publications

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NO<sub><i>x</i></sub> levels

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NO<sub><i>x</i></sub> levels

Mass concentration, optical depth and carbon composition of particulate matter in the major southern West African cities of Cotonou (Benin) and Abidjan (Côte d'Ivoire)

Quantification of environmentally persistent free radicals and reactive oxygen species in atmospheric aerosol particles

Contact Info

Product

Resources

About

Reactive Oxygen Species Production Mediated by Humic-like Substances in Atmospheric Aerosols: Enhancement Effects by Pyridine, Imidazole, and Their Derivatives

Abstract: 13Ambient particulate matter (PM) can cause adverse health effects via their ability to produce

Cited by 143 publications

References 43 publications

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NO&lt;sub&gt;&lt;i&gt;x&lt;/i&gt;&lt;/sub&gt; levels

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NO&lt;sub&gt;&lt;i&gt;x&lt;/i&gt;&lt;/sub&gt; levels

Mass concentration, optical depth and carbon composition of particulate matter in the major southern West African cities of Cotonou (Benin) and Abidjan (Côte d'Ivoire)

Quantification of environmentally persistent free radicals and reactive oxygen species in atmospheric aerosol particles

Contact Info

Product

Resources

About

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NO<sub><i>x</i></sub> levels

Dithiothreitol activity by particulate oxidizers of SOA produced from photooxidation of hydrocarbons under varied NO<sub><i>x</i></sub> levels