Reactivity of mixed organozinc and mixed organocopper reagents: 12 . Three component reaction of mixed (n-alkyl)(diaryl)zincates, chloroformates and phosphines for the synthesis of esters

Reactivity of mixed organozinc and mixed organocopper reagents: 14. Phosphine-nickel catalyzed aryl-allyl coupling of (n-butyl)(aryl)zincs. Ligand and substrate control on the group selectivity and regioselectivity

“…Theoretical studies on the control of group selectivity have been reported by Nakamura [32,33] and experimental studies on the effects of organyl groups on the reactivity and selectivity of mixed cuprates have been reported by Bertz [34] and Nakamura [35]. Our group carried out a series of synthetic and mechanistic work [36e40] on the reactivity and group selectivity of mixed diorganozincs, R 1 R 2 Zn [36]; mixed diorganocuprates, R 1 R 2 CuM (M ¼ MgBr [37], ZnCl [38]) and Cu catalyzed mixed triorganozincates, R 1 (R 2 ) 2 ZnMgBr [38] in their CeC [36], C-COR [39], C-COOR [38] and CeN coupling [40] reactions. We showed that the group selectivity of both mixed diorganocuprates and diorganozincs can be controlled by changing reaction parameters, i.e.…”