This paper introduces the principle of a radio frequency identification (RFID) middleware, including its characteristics, problems and implementation in relation to Electronic Product Code (EPC). The targeted users are small and medium-sized domestic enterprises (SMEs), who need flexible and convenient solutions. This paper provides a framework and construction solutions of this simple RFID middleware, and discusses EPC concepts, solutions and advantages. It has been found that the best solution is to construct a simple and convenient platform and continuously add new common reader adapters based on the actual needs and extend special applications, which will become the basic functions of the RFID middleware, so that SMEs can conveniently use and extend these functions according to their needs. This study shows that the simple RFID middleware is suitable for SMEs to use and the open source can be easily applied to make a platform based on the RFID middleware.