Reading virtual slide using web viewers: results of subjective experience with three different solutions

Rojo, Marcial García; Gallardo, Antonio José; González, Lucía Gómez; Peces, Carlos; Murillo, Cristina; González, Jesús Eduardo Aguilera; Sacristán, José Gimeno

doi:10.1186/1746-1596-3-s1-s23

Cited by 8 publications

(4 citation statements)

References 2 publications

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“…There is also the Integrating the Healthcare Enterprise effort to come up with a general pathology workflow based on DICOM and HL7 [22]. Some vendors are implementing functionality to be able to read each other's slides [23], but having one open and generic standard would eliminate this need.…”

Section: Discussionmentioning

confidence: 99%

Creation of a fully digital pathology slide archive by high-volume tissue slide scanning

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Creation of a fully digital pathology slide archive by high-volume tissue slide scanning

et al. 2010

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“…From the theoretical point of view, the diagnostic judgment in tissue based diagnosis can be distinguished in a) selection of the ROI, and b) the diagnostic statement [ 12 , 28 - 31 ]. In surgical pathology both algorithms are usually performed in only one combined step.…”

Section: Discussion and Perspectivesmentioning

confidence: 99%

Virtual slides in peer reviewed, open access medical publication

et al. 2011

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BackgroundApplication of virtual slides (VS), the digitalization of complete glass slides, is in its infancy to be implemented in routine diagnostic surgical pathology and to issues that are related to tissue-based diagnosis, such as education and scientific publication.ApproachElectronic publication in Pathology offers new features of scientific communication in pathology that cannot be obtained by conventional paper based journals. Most of these features are based upon completely open or partly directed interaction between the reader and the system that distributes the article. One of these interactions can be applied to microscopic images allowing the reader to navigate and magnify the presented images. VS and interactive Virtual Microscopy (VM) are a tool to increase the scientific value of microscopic images.Technology and PerformanceThe open access journal Diagnostic Pathology http://www.diagnosticpathology.org has existed for about five years. It is a peer reviewed journal that publishes all types of scientific contributions, including original scientific work, case reports and review articles. In addition to digitized still images the authors of appropriate articles are requested to submit the underlying glass slides to an institution (DiagnomX.eu, and Leica.com) for digitalization and documentation. The images are stored in a separate image data bank which is adequately linked to the article. The normal review process is not involved. Both processes (peer review and VS acquisition) are performed contemporaneously in order to minimize a potential publication delay. VS are not provided with a DOI index (digital object identifier). The first articles that include VS were published in March 2011.Results and PerspectivesSeveral logistic constraints had to be overcome until the first articles including VS could be published. Step by step an automated acquisition and distribution system had to be implemented to the corresponding article. The acceptance of VS by the reader is high as well as by the authors. Of specific value are the increased confidence to and reputation of authors as well as the presented information to the reader. Additional associated functions such as access to author-owned related image collections, reader-controlled automated image measurements and image transformations are in preparation.Virtual SlidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1232133347629819.

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“…Virtual microscopy (VM) is a technology in which glass slides are scanned and converted into digital images. [ 1 – 3 ] These digital images are stored, viewed, and screened on the computer using a mouse. This technology is widely used in medical student education in pathology, continuing education, histopathology, cytology, veterinary and comparative pathology, and hematology.…”

Section: Introductionmentioning

confidence: 99%

Virtual microscopy in cytotechnology education: Application of knowledge from virtual to glass

et al. 2012

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Background:Virtual microscopy (VM) is a technology in which the glass slides are converted into digital images. The main objective of this study is to determine if cellular morphology, learned through virtual microscopy, can be applied to glass slide screening.Materials and Methods:A total of 142 glass slides (61 teaching and 81 practice) of breast, thyroid, and lymph node fine needle aspiration body sites were scanned with a single focal plane (at 40X) using iScanCoreo Au (Ventana, Tuscan, AZ, USA, formerly known as BioImagene, California, USA). Six students including one distant student used these digital images to learn cellular morphology and conduct daily screening. Subsequently, all the students were tested on 10 glass slides using light microscopy (LM). At the end of the study, the students were asked to respond to an online survey on their virtual microscopy experience. The glass slide screening test scores of the participating students who were taught through VM and tested on glass slides (VMLM group) were compared with the last three classes of students who were taught through LM and tested on glass slides (LMLM group).Results:A non-parametric statistical analysis indicated no difference (P= 0.20) in the glass screening test scores between VMLM (median = 93.5) and LMLM groups (median = 87). The survey indicated that the annotated teaching slides and access to the VM, off campus, were well appreciated by the students.Conclusions:Although the students preferred LM, they were able to apply the cytological criteria learned through VM to glass slide screening. Overall, VM was considered a great teaching tool.

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Reading virtual slide using web viewers: results of subjective experience with three different solutions

Cited by 8 publications

References 2 publications

Creation of a fully digital pathology slide archive by high-volume tissue slide scanning

Creation of a fully digital pathology slide archive by high-volume tissue slide scanning

Virtual slides in peer reviewed, open access medical publication

Virtual microscopy in cytotechnology education: Application of knowledge from virtual to glass

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