Readmissions after Pancreatic Surgery in Patients with Pancreatic Cancer: Does Hospital Variation Exist for Quality Measurement?

Abstract

Background: The appropriateness of using readmission rate after pancreatic surgery among pancreatic cancer patients as a quality metric to evaluate hospital performance has been widely discussed in the literature. Objectives: The present study reported readmission rate using Nationwide Readmissions Database (NRD), examined the reasons and risk factors for readmissions, and evaluated the appropriateness of using it as a quality metric. Method: We analyzed 3,619 patient discharge records in 2014. The outcome of interest was all-cause 30-day readmission. Reasons for readmission were grouped into clinical associated categories. Hierarchical regression model was used for examining the relationship between risk factors and readmission. Results: The 30-day readmission rate was 20.95%. The most common reason for readmission was surgery-related complication. In descriptive analyses, age, certain comorbidities, number of chronic conditions, mortality risk, severity of illness, living at large metropolitan area, resident of the state where patients received initial care, postoperative complication, length of stay, discharge location, and receiving care at the hospitals in large metropolitan area were predictive of readmission. In multivariable analysis, age, depression, peripheral vascular disorder, mortality risk, and discharge location were independently associated with readmission. The intraclass correlation coefficient was 0.41 for hierarchical regression model. Conclusions: Readmission after pancreatic surgery remains an important issue. Our study found the majority of variation in readmissions is accounted for by patient factors whereas there was little between hospital variation. This finding does not support the use of readmission rate after pancreatic surgery as a quality metric.

The Implications of Readmission on Cost and Patient Outcomes Following Distal Pancreatectomy and Splenectomy

“…Identifying factors to minimize readmissions may help reduce its incidence. 16,17 Targeting postoperative care, discharge care, and patient education can help reduce readmission frequency. One notable proactive approach and future study could focus on engaging patients in comprehensive preoperative education sessions conducted by a nurse educator or through a preoperative clinic.…”

E3 ubiquitin ligase TRIM29 promotes pancreatic cancer growth and progression via stabilizing Yes-associated protein 1

“…PC is a highly malignant neoplasm with poor prognosis. Due to the majority of patients are diagnosed at a later or metastatic stage, only no more than 20% of pancreatic cancer patients are resectable [20,21]. Targeted tumour therapy and neoadjuvant chemotherapy play important roles in inhibiting the progression of PC.…”

E3 Ubiquitin Ligase TRIM29 Promotes Pancreatic Cancer Growth and Progression via Stabilizing Yes-associated Protein 1

“…Surgery remains the only way to treat PC. However, most patients are diagnosed at a middle or advanced stage and lose the opportunity for a radical surgery [19,20]. Although great progress has been made in surgical procedures, the prognosis of PC has not made great breakthroughs.…”