Real case of primitive embryonal duodenal carcinoma in a young man

Abstract

We report here the case of a young man suffering from a rare germ cell tumour. The patient was a 25-year-old man who was referred to our centre for asthenia, stinging epigastric pain, and an iron deficiency anaemia. Gastroscopy revealed a circumferential vegetating lesion on the second portion of the duodenum. The lesion was indurated at the third portion of the duodenum, responsible for a tight stenosis. A computerized tomography-scan of the chest, abdomen and pelvis, and a pancreatic MRI showed a circumferential lesion with a bi-ductal dilatation (i.e., of the common bile duct and Wirsung’s duct) without metastatic localisation. The patient underwent a pancreaticoduodenectomy with lymph node dissection including all cellular adipose tissues of the hepatic pedicle from the hepatic common artery and of the retroportal lamina. Histological findings were suggestive of a duodenal embryonal carcinoma with pancreatic infiltration. This is the second published case highlighting the duodenal primitive localisation of an embryonal carcinoma with pancreatic infiltration.

Primary Duodenal Carcinoma with Embryonal Carcinoma Features in a Young Man

“…This is a case of primary duodenal cancer with unusual characteristics of embryonal carcinoma. Embryonal carcinoma of the duodenum is rare and is not often reported as a primary tumor [ 8 ]. In most cases of metastatic duodenal germ cell tumors (GCTs), the images appear to be clustered with swollen lymph nodes of the retroperitoneum.…”