Real-life prospective study on asthma control in Italy: Cross-sectional phase results

Abstract

Asthma control is achieved in a good proportion of Italian patients. Differences may be detected in a real-life setting in favor of extrafine beclomethasone/formoterol combination.

Assessing and accessing the small airways; implications for asthma management

“…In this real life setting, the proportion of patients achieving asthma control was significantly higher in the BDP/F extrafine group than in the non-extrafine BUD/F or FP/S group, and this was achieved with a significantly lower ICS mean daily dose [77]. This was confirmed in a recently published large observational study, showing that the extrafine BDP/F combination resulted in better asthma control and quality of life compared to non-extrafine formulations [78]. However, it remains to be established whether the addictive effect of extrafine formulations compared to no extrafine formulations on asthma control is related to the small airways targeting or whether may represent a consequence of a better distribution of the delivered drugs throughout the bronchial tree.…”

Control of asthma in adults treated with beclomethasone and formoterol in extrafine particle formulation in a real-life setting in Poland: the CASPER noninterventional, observational trial

“…15,16 According to previous study results, the BDP/F-pMDI HFA proved more effective in achieving asthma control and resulted in improved quality of life. [16][17][18] The objective of this noninterventional study was to assess long-term asthma control, the patient's opinion on the pMDI and satisfaction with therapy, and safety of the extrafine aerosol formulation of the BDP/F combination in a real-life setting in Poland. The effect of training in the correct inhaler technique on asthma control in patients was also assessed.…”

The Life's Limitations of Uncontrolled Asthma in a Developing Country: Results of an Albanian Survey

“…The general attitude of Albanian asthmatics shows a similarity towards Europeans with severe BA in the industrialized countries [2][3][4][5][6][7][8][9][10][11]. These findings suggest that in our country patients with uncontrolled asthma represent the majority, and that Albanian (predominantly male) patients consider their BA as a disease only if they experience uncontrolled symptoms and daily restrictions.…”

“…In comparison to industrialized European countries (IECs), the proportion of patients with uncontrolled or severe BA is quite greater [2,7]. In Italy, a neighbor land of Albania, among 2853 recruited adult patients, 64% had controlled BA, 16% partly controlled BA and only 20% were with uncontrolled BA [5]. Meanwhile, one-third of patients with respiratory allergic diseases recruited in ten different IECs were not satisfied with their treatment, and two-thirds experienced restrictions in daily activities [2,7,10].…”

“…BA is controllable when patients adhere to the correct treatment according to respective management guidelines [3][4][5]. In industrialized countries, severe persistent BA is associated with a particularly high exacerbation's risk, Most surveys across Europe provide data from industrialized or advanced developing countries, but there is a lack of published data from countries with poor socio-economical situation of the same regional and ethnic populations [2,5,[7][8][9][10][11]. We report about the outcomes of an Albanian survey, focused on the opinions of subjects with uncontrolled BA, providing also insight into the level of their lives affection.…”