Real-time analysis of magnetic nanoparticle clustering effects by inline-magnetic particle spectroscopy

Key Contributors to Signal Generation in Frequency Mixing Magnetic Detection (FMMD): An In Silico Study

“…The present study identifies key input parameters contributing to FMMD signal generation from isolated parameter variation; however, the following limitations are faced, which we will directly turn into potential improvements for future investigations: As identified in Section 4.1 (discussing the -dependence), the present simulation framework does not consider particle agglomeration/clustering. However, it is becoming more and more evident that agglomerations (or clusters) play a significant role in MNP systems, either globally (non-directional) [ 62 , 63 ] or as a precondition by purposeful alignment of MNP [ 64 , 65 ]. Recently, it has been demonstrated that agglomeration in a similar simulation framework can be included [ 66 ].…”

“…As identified in Section 4.1 (discussing the -dependence), the present simulation framework does not consider particle agglomeration/clustering. However, it is becoming more and more evident that agglomerations (or clusters) play a significant role in MNP systems, either globally (non-directional) [ 62 , 63 ] or as a precondition by purposeful alignment of MNP [ 64 , 65 ]. Recently, it has been demonstrated that agglomeration in a similar simulation framework can be included [ 66 ].…”

Progress and opportunities for metal–organic framework composites in electrochemical sensors

“…Owing to their large specific surface area, abundant active centers, high catalytic efficiency, and good adsorption capacity, magnetic nano-materials have been thoroughly investigated and widely applied. 125–127 Fe 3 O 4 is one of the most widely used magnetic nano-materials because MOF/Fe 3 O 4 composites exhibit the synergistic effect of MOF and Fe 3 O 4 , and can effectively prevent agglomeration of these composites. Consequently, MOF/Fe 3 O 4 composites show excellent potential for electrochemical sensing.…”

“…Owing to their large specic surface area, abundant active centers, high catalytic efficiency, and good adsorption capacity, magnetic nano-materials have been thoroughly investigated and widely applied. [125][126][127] Chang et al 128 polymerized DA onto the surface of Fe 3 O 4 nanoparticles, and then combined it with CuSO 4 and H 3 BTC to prepare magnetic Fe 3 O 4 @PDA@MOF material, which was applied to construct Fe 3 O 4 @PDA@MOF@MIP electrochemical sensor for detecting oxytetracycline. The introduction of MOF can increase the surface area of Fe 3 O 4 nanoparticles, thus increasing the number of pores and effective binding sites of MIP, so that the sensor has an obvious electrochemical response to tetracycline.…”