“…Indeed, pressures may behave differently depending on its proximity to the central nervous system or the shape and size of the peripheral nerve, among other things. Likewise, aspects that do not relate to injection location, such as needle diameter and length, and the force applied to the injection, may influence the resulting pressure curves 4–6. Efforts must continue to determine the behavior of pressures and their relationship with the compliance of the different human compartments 4 7.…”