The need to tunnel closely beneath piles is increasing due to the development of urban areas. This poses a risk to the stability and serviceability of overlying structures (e.g. buildings, piers, piled embankments). The impact of tunneling on piles is usually assessed using a displacement threshold, yet this provides no information about the post-tunneling pile safety factor. Knowledge of a pile's safety factor under serviceability or extreme loading conditions is important, especially if future re-purposing of the associated superstructure is a possibility. Tunneling can reduce the safety factor of a pile up to the point of geotechnical failure (i.e. when the pile capacity reduces to that of the applied load), yet little guidance is available to enable a straightforward means of assessing the post-tunneling safety factor of a pile. This paper aims to address this shortcoming by providing design charts based on an analytical tunnel-single pile interaction approach that provides a means of determining post-tunneling pile safety factor. The methodology and design charts are applicable to drained soil conditions and include for the effects of initial pile safety factor, pile installation method (displacement (driven and jacked), non-displacement (bored) with only shaft capacity, and 1 Marshall et al. non-displacement with base and shaft capacity), and varying water table depth. In the paper, as a validation exercise, analytical predictions are compared against data from geotechnical centrifuge tests designed to model both displacement and non-displacement piles in sands, including a variety of tunnel-pile relative locations and initial pile safety factors. For a specified design value of post-tunneling pile safety factor, the design charts enable a quick assessment of the safe location of a pile or tolerable tunnel volume loss considering ground parameters, water table position, pile installation method, and initial safety factor.