Real Time Implementation of a Wiener Filter Based Crystal Identification Algorithm

Viscogliosi, N.; Riendeau, J.; Bérard, P.; Tetrault, M.-A.; Lefebvre, Rémi; Fontaine, R.

doi:10.1109/tns.2008.922815

Cited by 27 publications

(19 citation statements)

References 9 publications

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“…Each APD is coupled to a LYSO and a LGSO crystal. Due to the different timing properties of LYSO and LGSO, the origin of a light pulse can be determined from the pulse shape [8]. This leads to effective one-to-one coupling.…”

Section: A Equipmentmentioning

confidence: 99%

Absolute quantification for small-animal PET

Keereman

Holen

Vanhove

et al. 2011

2011 IEEE Nuclear Science Symposium Conference Record

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Abstract-Quantification is important in preclinical PET studies. To achieve absolute quantification, an accurate reconstruction algorithm is necessary. Such an algorithm includes corrections for different effects such as geometric sensitivity of the scanner, detection efficiency, attenuation, scatter and random coincidences. In this work we present a method for performing absolute quantification on the LabPET system. All acquisitions were done on a GE Triumph system. This tri-modality system consists of a micro-PET (LabPET), micro-CT (X-O) and micro-SPECT (X-SPECT) scanner. Three PET scans were done. In the first scan 5 vials with different activity concentrations of 18 F-FDG were scanned. The total activity inside the scanner was 80 MBq. The second scan was performed after 4 hours when the total activity in the scanner had decayed to 20 MBq. In the third scan 3 vials and 1 sphere were scanned with a total activity of 20 MBq. Before each PET scan a micro-CT scan was acquired.Point sources with a known activity were placed inside the field of view. The counts obtained in these point sources are used to obtain a correction factor for absolute sensitivity. Reconstruction was done using a 3D ML-EM reconstruction with micro-CT based attenuation correction. VOIs were drawn over the vials and the sphere in the reconstructed images. The total activity in the VOIs was calculated using the correction factor for absolute sensitivity. It was compared to the activity measured in a dose calibrator.The average quantification error was 56 %, 6.4 % and 0.6 % for the first, second and third scan. The high error in the first scan is explained by count rate effects, as 80 MBq can be considered a high activity level for this system.The feasibility of absolute quantification on the LabPET system was demonstrated. When the count rate is below 20 MBq absolute quantification is possible with an average quantification error smaller than 6.4 %.

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Section: A Equipmentmentioning

confidence: 99%

Absolute quantification for small-animal PET

Keereman

Holen

Vanhove

et al. 2011

2011 IEEE Nuclear Science Symposium Conference Record

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“…Crystal identification of the LGSO phoswich assemblies was investigated using a conventional PSD technique based on standard NIM analog electronics and using the LabPET acquisition system implementing advanced digital PSD algorithms [23], [24]. The conventional analog method was used as a reference to assess the crystal identification accuracy achievable with the most promising crystal pair.…”

Section: Pulse Shape Discrimination Measurementsmentioning

confidence: 99%

Characteristics of Lu$_{1.8}$Gd$_{0.2}$SiO$_{5}$:Ce (LGSO) for APD-Based PET Detector

Shimizu

Pépin

Bergeron

2010

IEEE Trans. Nucl. Sci.

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Since its discovery in 1993, LGSO has been seen as a promising scintillator for positron emission tomography (PET) imaging. Recently, new high lutetium content Lu 1 8 Gd 0 2 SiO 5 :Ce (LGSO-90%Lu) has been produced with Ce concentration varying from 0.025 to 0.75 mol% Ce, yielding decay times in the range of 34.2 to 44.8 ns. These scintillators could potentially be used as phoswich detectors in PET for improving spatial resolution. To validate this assumption, light output, energy resolution, temperature dependence, timing resolution, and pulse-shape discrimination performance were assessed. The light output of these LGSO scintillators is 3.5 to 4.8 times higher than BGO with avalanche photodiode readout [7.5 to 8 times with photomultiplier tube (PMT)] and increases with Ce concentration. The variation of light output for temperature ranging from 10 to 50 C is less than 18% with PMT readout. Energy resolution at 662 keV is about 11% (l0%) with avalanche photodiode (APD) (PMT) readout. Timing resolution with APD is 1.65 ns for all samples relative to a fast PMT-plastic detector. Pulse-shape discrimination of LGSO-90% Lu with 0.025 mol% Ce ( = 34 2 ns) and 0.75 mol% Ce ( = 44 8 ns) was successfully achieved in a phoswich assembly, making this new high lutetium content LGSO with adjustable decay time constants a strong candidate for a high-resolution depth-of-interaction detector intended for PET imaging.

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“…The cross-correlation method, like another CI method measurement, is sensible to signal phase difference [5,6]. To overcome this aforementioned limitation, we interpolate the signal f (n) with a technique called cubic spline interpolation.…”

Section: Cross-correlation-based Crystal Identificationmentioning

confidence: 99%

“…Among these methods, the pulse shaping discrimination (PSD), which is sensitive to noise, uses temporal or frequency features of the extracted signal for identification [3]. On the other hand, the auto-regressive with exogenous variable (ARX) model [4] or its fast version, the auto-regressive (AR) model [5,6], extract the decay time by using an adaptive filter. They present a higher immunity to noise, but at a higher computational burden when compared to PSD.…”

Section: Introductionmentioning

confidence: 99%