Real-time Measurement System for Evaluation of the Carotid Intima-Media Thickness With a Robust Edge Operator

Faita, Francesco; Gemignani, V.; Bianchini, Elisabetta; Giannarelli, Chiara; Ghiadoni, Lorenzo; Demi, M.

doi:10.7863/jum.2008.27.9.1353

Cited by 127 publications

(114 citation statements)

References 15 publications

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“…ear old TUFFC D [10,12] , e CCA e CCA for the studies [15] , the ages of es were ntation 15,21] , a butions MC was ke were ynamic sented. nted in ue from [18] and ore still ntioned techniques in a more atheroscler…”

Section: -939xmentioning

confidence: 99%

An integrated system for the complete segmentation of the common carotid artery bifurcation in ultrasound images

Loizou

Pantziaris

2015

JBEI

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The complete segmentation of the common carotid artery (CCA) bifurcation in ultrasound images is important for the evaluation of atherosclerosis disease and the quantification of the risk of stroke. The current research work further evaluates and validates a semi-automated (SA) snake's based segmentation system suitable for the complete segmentation of the CCA bifurcation in two-dimensional (2D) ultrasound images. The proposed system semi-automatically estimates the intima-media thickness (IMT), the atherosclerotic carotid plaque borders and dimensions, the internal carotid artery (ICA) origin's stenosis, the carotid diameter (D), as well as other geometric measurements of the atherosclerotic carotid plaque. The system was evaluated on 300 2D longitudinal ultrasound images of the CCA bifurcation with manual (M) segmentations available from a neurovascular expert. No statistical significant differences between all M and SA IMT, plaque and D segmentation measurements were found. In a future study, texture features extracted from the intima-media complex (IMC) may be used to separate subjects in high and low risk groups, which may develop a stroke. However, a larger scale study is required for evaluating the system before its application in the real clinical practice.

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Section: -939xmentioning

confidence: 99%

An integrated system for the complete segmentation of the common carotid artery bifurcation in ultrasound images

Loizou

Pantziaris

2015

JBEI

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“…We ran the semiautomated FOAM as a standalone on our 665-image database and obtained an average IMT value of 0.804 ± 0.243 mm, with an IMT measurement bias of 0.001 ± 0.223 mm when compared to reader 1 and 0.032 ± 0.255 mm when compared to reader 2. Therefore, on our multi-institutional database, we could not obtain the same performance Faita et al 25 obtained on their single-institution data set. Our explanation is that we worked on a multi-institutional database consisting of images with different pixel densities (Table 1) and noise levels.…”

Section: Discussionmentioning

confidence: 51%

“…The best performing computer method we found in the literature was the semiautomated technique by Faita et al, 25 which was based on FOAM. They obtained an average IMT measurement error of about 0.010 ± 0.038 mm.…”

Section: Discussionmentioning

confidence: 99%

“…The FOAM operator enhances the image edges and is very robust with respect to noise. 25,26 This factor ensures good robustness to noise and artifacts.…”

Section: Discussionmentioning

confidence: 99%

“…They obtained an average IMT measurement error of about 0.010 ± 0.038 mm. The FOAM-based technique by Faita et al 25 was user driven: the reader had to select a region of interest around the distal wall, where the IMT measurement was then performed by using FOAM. We ran the semiautomated FOAM as a standalone on our 665-image database and obtained an average IMT value of 0.804 ± 0.243 mm, with an IMT measurement bias of 0.001 ± 0.223 mm when compared to reader 1 and 0.032 ± 0.255 mm when compared to reader 2.…”

Section: Discussionmentioning

confidence: 99%

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Fully Automated Dual-Snake Formulation for Carotid Intima-Media Thickness Measurement

Molinari

Meiburger

Saba

et al. 2012

Journal of Ultrasound in Medicine

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A New Approach he intima-media thickness (IMT) of the carotid arteries is a validated predictor of cardiovascular accidents 1 and is associated with several cardiovascular diseases. [2][3][4][5][6] In clinical practice, the sonographer usually manually measures the IMT value during the examination. 7 By means of the scanner calipers, the sonographer places two markers corresponding to the lumen-intima (LI) and media-adventitia (MA) interfaces. The distance between the markers is the estimation of the IMT. However, as Polak et al 8 recently showed, the inter-reader variability in IMT measurements could cause a substantial bias in the estimation of a patient 's Filippo Molinari, PhD, Kristen M. Meiburger, MSc, Luca Saba, MD, Guang Zeng, PhD, U. Rajendra Acharya, PhD, Mario Ledda, MD, Andrew Nicolaides, PhD, Jasjit S. Suri, PhD, MBA, FAIMBE Received August 30, 2011, from BioLab, Department TECHNICAL INNOVATIONAutomated computer-aided detection systems for measurement of the carotid intimamedia thickness (IMT) are becoming popular. These systems yield lumen-intima (LI) and media-adventitia (MA) borders. In this work, we developed and validated a novel and patented completely automated IMT measurement system called carotid measurement using dual snakes (CMUDS): a class of AtheroEdge system (Global Biomedical Technologies, Inc, Roseville, CA). CMUDS is modeled as a dual parametric system corresponding to LI and MA borders with initialization from the far adventitia layer. The novelty of CMUDS is the first-order absolute moment-based external energy, which provides stable deformation. The dual snakes evolve simultaneously and are forced to maintain a regularized distance to prevent collapsing or bleeding. Two independent readers manually traced the LI/MA boundaries of a multi-institutional, multiethnic, and multi-scanner database of 665 longitudinal images for performance evaluation. CMUDS was also benchmarked against a previously developed automated technique. CMUDS correctly processed 660 images (99.2% success). The differences between the CMUDS and two manual IMT measurements (mean ± SD) were 0.013 ± 0.216 and -0.021 ± 0.197 mm, respectively. The corresponding figures of merit for CMUDS compared to reader tracings were 98.4% and 97.5%. Compared to the previous technique (IMT differences, 0.022 ± 0.276 and -0.012 ± 0.266 mm), CMUDS improved accuracy (Wilcoxon P < 0.009) and variability (Fisher P < 10 -8 ). Among different resolution images from original equipment manufacturer ultrasound scanners, CMUDS performed best with high-resolution images corresponding to 0.0789 mm/pixel. Accuracy in IMT measurement with the proposed automated CMUDS technique makes this system adaptable to large multi-center studies, in which such an IMT measurement system would be very useful tool.

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Fully automated on‐screen carotid intima‐media thickness measurement: A screening tool for subclinical atherosclerosis

Vanoli

Lindqvist

Wiklund

et al. 2013

J of Clinical Ultrasound

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Real-time Measurement System for Evaluation of the Carotid Intima-Media Thickness With a Robust Edge Operator

Cited by 127 publications

References 15 publications

An integrated system for the complete segmentation of the common carotid artery bifurcation in ultrasound images

An integrated system for the complete segmentation of the common carotid artery bifurcation in ultrasound images

Fully Automated Dual-Snake Formulation for Carotid Intima-Media Thickness Measurement

Fully automated on‐screen carotid intima‐media thickness measurement: A screening tool for subclinical atherosclerosis

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