Real Time PCR for the Evaluation of Treatment Response in Clinical Trials of Adult Chronic Chagas Disease: Usefulness of Serial Blood Sampling and qPCR Replicates

Abstract

23This work evaluated a serial blood sampling procedure to enhance the sensitivity of duplex collected during the same day and the third one seven days later. 31A patient was considered PCR positive if at least one qPCR replicate was detectable. 32Cumulative results of multiple samples and qPCR replicates enhanced the proportion of pre-