An accurate wind speed prediction system is of great importance prerequisite for realizing wind power grid integration and ensuring the safety of the power system. Quantifying wind speed fluctuations can better provide valuable information for power dispatching. Therefore, this paper proposes a deterministic wind speed prediction system and an interval prediction method based on the Lorentzian disturbance sequence. For deterministic forecasting, a variational modal decomposition algorithm is first used to reduce noise. The preprocessed data are then predicted by a long and short-term neural network, but there is a significant one-step lag in the results. In response to such limitation, a wind speed slope is introduced to revise the preliminary prediction results, and the final deterministic wind speed prediction model is obtained. For interval prediction, on the basis of deterministic prediction, the Lorenz disturbance theory is introduced to describe the dynamic atmospheric system. B-spline interpolation is used to fit the distribution of Lorenz disturbance theory series to obtain interval prediction results. The experimental results show that the model proposed in this paper can achieve higher forecasting accuracy than the benchmark model, and the interval prediction based on the Lorentzian disturbance sequence can achieve a higher ground truth coverage rate when the average diameter is small through B-spline interpolation fitting.