Online monitoring of population traffic within a certain region plays a significant role in modern city administration and public security, and it is also a difficult task to fulfil using traditional methods. In this paper, a system is reported, which has realized fast estimation of snapshot population and residence time distribution within a certain region, based on mobile network signaling. The system architecture is presented and some key implementation issues are addressed. As examples, results in two typical regions are demonstrated and thoroughly compared. One is a historical attraction, and the other is a traffic junction in the central business area. The system has currently come into operation in Beijing and begun serving several municipal departments including tourism, administration and public security.