Real-world effectiveness and safety of sensor-augmented insulin pump therapy in adults with type 1 diabetes: Long-term follow-up

Coronel-Restrepo, Nicolás; Blanco, V. M.; Palacio, Andrés; Rincón, Alex Ramírez; Arbeláez, Sebastián; Duque, Valentina; Pino, Juan José; Carvajal, Javier; Bedoya, Jorge; Cuesta, Diana; Botero, José Fernando

doi:10.1016/j.endien.2021.11.009

Cited by 1 publication

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Automated insulin suspension systems allow the insulin pump to suspend basal insulin delivery in response to either a current low glucose concentration or prediction of an impending hypoglycemic event, as identified by CGM. Automated insulin suspension has been shown to reduce HbA1c [63,64], hypoglycemia [65][66][67][68], and patient-reported fear of hypoglycemia [69].…”

Section: Evolution Of Device Collaborationmentioning

confidence: 99%

Continuous Glucose Monitor, Insulin Pump, and Automated Insulin Delivery Therapies for Type 1 Diabetes: An Update on Potential for Cardiovascular Benefits

et al. 2022

View full text Add to dashboard Cite

Purpose of Review The incidence of type 1 diabetes (T1D) is rising in all age groups. T1D is associated with chronic microvascular and macrovascular complications but improving glycemic trends can delay the onset and slow the progression of these complications. Utilization of technological devices for diabetes management, such as continuous glucose monitors (CGM) and insulin pumps, is increasing, and these devices are associated with improvements in glycemic trends. Thus, device use may be associated with long-term prevention of T1D complications, yet few studies have investigated the direct impacts of devices on chronic complications in T1D. This review will describe common diabetes devices and combination systems, as well as review relationships between device use and cardiovascular outcomes in T1D. Recent Findings Findings from existing cohort and national registry studies suggest that pump use may aid in improving cardiovascular risk factors such as hypertension and dyslipidemia. Furthermore, pump users have been shown to have lower arterial stiffness and better measures of myocardial function. In registry and case–control longitudinal data, pump use has been associated with fewer cardiovascular events and reduction of cardiovascular disease (CVD) and all-cause mortality. Summary CVD is the leading cause of morbidity and mortality in T1D. Consistent use of diabetes devices may protect against the development and progression of macrovascular complications such as CVD through improvement in glycemic trends. Existing literature is limited, but findings suggest that pump use may reduce acute cardiovascular risk factors as well as chronic cardiovascular complications and overall mortality in T1D.

show abstract