Real-world evaluation of COVID-19 lateral flow device (LFD) mass-testing in healthcare workers at a London hospital; a prospective cohort analysis

Abstract

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The clinical utility and epidemiological impact of self-testing for SARS-CoV-2 using antigen detecting diagnostics: a systematic review and meta-analysis

“…Most of the datasets were from the United Kingdom (8; 47.1% of all data sets) [15,16,28,29,33,34], and the others from Germany (4; 23.5% of all data sets) [17,27,32], Austria (3; 17.6% of all data sets) [31], and the Netherlands (2; 11.8% of all data sets) [30]. In eight data sets (47.1% of all data sets) [15,16,28,29,33,34], the Innova SARS-CoV-2 Rapid Antigen Self-Test Kit (Innova Medical Group Inc., United States [CA]; henceforth called ‘Innova’) was used. The STANDARD Q COVID-19 Ag Home Test (SD Biosensor, South Korea; distributed in Europe by Roche, Germany; henceforth called ‘Standard Q’) [30,35] and the SARS-CoV-2 Antigen Rapid Test Kit (Lepu Medical Technology, China) [31] were used in three data sets each (17.6% of all data sets).…”

“…In 14 datasets (77.8% of all datasets) [15-17,27-29,31-34], C19ST was implemented as part of a routinely testing service, most often (4 datasets) [29,31,33,34] for testing twice weekly. C19ST was mainly performed at home (10 data sets; 58.8%), but also in school (4; 23.5% of all data sets) [27,31] or at work (1; 5.9% of all data sets) [34].…”

“…[NJ]) [30], another the RIDA QUICK SARS-CoV-2 Antigen (R-Biopharm, German) [32] and for the third the Ag-RDT used was unclear [27]. In eleven data sets (64.7% of all data sets), the sample type was anterior nasal / mid-turbinate (AN/MT) [28][29][30][31][32][33]35 [29,31,33,34] for testing twice weekly.…”

“…Overall, studies achieved a median of three ( Two datasets (11.8%) excluded persons who had a positive SARS-CoV-2 test result within the previous two months [27,29], enhancing comparability between study populations.…”

Implementation study of SARS-CoV-2 antigen lateral flow tests in men's professional (Premiership) rugby union sports squads in England during the COVID-19 pandemic

“…There was an urgent need to review the testing programme in Professional Rugby to agree the most cost-effective and accurate testing modality. We read with interest the real-world evaluation of antigen-based rapid diagnostic tests (Ag-RDTs) for COVID-19 and the high uptake for mass testing amongst healthcare workers [5] . To provide oversight, advice, and guidance on the scope of testing for SARS-CoV-2 by Ag-RDT, Premiership Rugby and Rugby Football Union approved this rapid collaborative service evaluation.…”