2023
DOI: 10.1200/jco.2023.41.16_suppl.e17055
|View full text |Cite
|
Sign up to set email alerts
|

Real-world genetic testing patterns in metastatic prostate cancer in Latin American (LATAM) population.

Abstract: e17055 Background: Prostate cancer (PC) clinical course is variable. It was thought that BRCA1 and BRCA2 mutations were associated with only a small proportion of PC cases. However, recent genomic analysis has revealed that germline or somatic inactivating mutations in genes involved in the homologous recombination (HR) pathway of DNA repair collectively occur in as much as 20%-25% of advanced PC. Referring to the metastatic castration resistant PC (mCRPC) the somatic mutations were recently reported to be up… Show more

Help me understand this report

This publication either has no citations yet, or we are still processing them

Set email alert for when this publication receives citations?

See others like this or search for similar articles