Real-World Insights in Thailand on Usage Satisfaction and Perceived Efficacy of Dexpanthenol in Nappy Care

Abstract

The prevalence of nappy rash or napkin dermatitis in Thailand infants aged 1–24 months is 36.1%. Dexpanthenol-containing nappy creams are clinical validated and effective in treating napkin dermatitis. This study explores the real-world usage satisfaction and perceived effectiveness of a 5% Dexpanthenol-containing product as a preventive strategy for napkin dermatitis. Respondents were mothers with babies between 6–12 months of age, who purchased and used a 5% Dexpanthenol-containing product (Bepanthen® Ointment) in the past one month. An online study collected respondents’ satisfaction with the product and its benefits and properties. A total of 300 respondents (52% frequent users and 48% as-needed users) completed the study. Over 90% of respondents reported that their babies experienced less nappy-related discomfort, crying, fidgeting and sleep disruption after applying the nappy care product. Almost all respondents (96%) were satisfied with the product. Notably, frequent users of the product reported higher rates of satisfaction than as-needed users (62% vs. 43%; p < 0.05). This high level of satisfaction was associated with the moisturizing properties and long-lasting skin protection provided by the dexpanthenol-containing product. Our findings from a real-world setting further validate the use of dexpanthenol-containing products as a preventive strategy for napkin dermatitis in Thai infants.

Evaluation of a 5% dexpanthenol‐containing ointment for the treatment of infant irritant diaper dermatitis through the lens of the caregiver—A real‐world data observational study

“…Discomfort and distress are common among infants with IDD, [8][9][10][11] and in our study, caregivers reported improvements relief of overnight discomfort, sleep disturbance, and overall discomfort following the application of the product.…”

“…Ointment preparations are water‐in‐oil emulsions with high lipid content (over 50% generally) and are the preferred galenic formulation for IDD management. Ointment preparations provide a durable barrier that is effective yet “breathable,” helping to maintain skin hydration while reducing diaper friction 3,8,23 . The efficacy and tolerability of Dexpanthenol‐containing ointment (DCO) have been demonstrated in controlled clinical settings for both treatment and prevention of infant IDD 23–27 .…”

“…3,4 IDD is characterized by reddening or scaling of the skin, which if untreated can progress to exudative or ulcerated lesions. [5][6][7] The condition can cause considerable discomfort to the baby, and can be distressing both to the infant, negatively impacting sleep and behavior, 8,9 and to the caregiver. 10,11 In most cases, IDD is managed by the caregiver rather than referred to a physician 1,6,12 ; hence, estimating the incidence of IDD is difficult.…”

“…Ointment preparations provide a durable barrier that is effective yet "breathable," helping to maintain skin hydration while reducing diaper friction. 3,8,23 The efficacy and tolerability of Dexpanthenol-containing ointment (DCO) have been demonstrated in controlled clinical settings for both treatment and prevention of infant IDD. [23][24][25][26][27] There remains, however, a lack of understanding of the caregivers' perspective about how they selfmanage the condition in a real-world setting.…”