2018
DOI: 10.1016/j.pcd.2018.06.001
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Real-world prevalence of mild to moderate hypoglycemic episodes in type 2 diabetes in Portugal: Results from the HIPOS-PHARMA study

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Cited by 10 publications
(17 citation statements)
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“…To date, data on hypoglycaemia are inconsistent and heterogeneous due to different study designs/data collection methods, hence it is difficult to compare our results with previous studies. However, a similar prevalence was observed in the Portuguese HIPOS‐PHARMA study . Although it has been reported that the risk of hypoglycaemia is not a significant concern with new glucose‐lowering drugs, attention is needed when combining these agents with secretagogues or insulin therapy , which was the case in the present study (a higher frequency of hypoglycaemic episodes was observed in the GLP‐1 receptor agonist subgroup, half of whom used insulin at cohort entry).…”
Section: Discussionsupporting
confidence: 81%
See 1 more Smart Citation
“…To date, data on hypoglycaemia are inconsistent and heterogeneous due to different study designs/data collection methods, hence it is difficult to compare our results with previous studies. However, a similar prevalence was observed in the Portuguese HIPOS‐PHARMA study . Although it has been reported that the risk of hypoglycaemia is not a significant concern with new glucose‐lowering drugs, attention is needed when combining these agents with secretagogues or insulin therapy , which was the case in the present study (a higher frequency of hypoglycaemic episodes was observed in the GLP‐1 receptor agonist subgroup, half of whom used insulin at cohort entry).…”
Section: Discussionsupporting
confidence: 81%
“…With regard to hypoglycaemic episodes, 22% of participants (95% CI [19][20][21][22][23][24] experienced at least one episode, with the majority of episodes classified as mild to moderate (21%; 95% CI [19][20][21][22][23]. Severe/very severe episodes were reported by 1.6% of participants (95% CI 0.9-2.3).…”
Section: Adverse Drug Event Occurrencementioning
confidence: 99%
“…Of the 12 studies included in this review, only 2 [ 26 , 27 ] investigated SHEs in patients with T1DM. In the remaining studies, three focused on T2DM [ 24 , 25 ] and seven reported data on both T1DM and T2DM [ 11 , 23 , 25 , 28 , 30 – 32 ].…”
Section: Resultsmentioning
confidence: 99%
“…HypoglycemIa in POrtugal Study (HIPOS) was a sequence of three observational studies to capture the overall panorama of hypoglycemia events in Portugal in different settings of healthcare assistance: ambulatory (HIPOS-PHARMA) [ 16 ], emergency room (HIPOS-ER) [ 17 ], and hospitalizations (HIPOS-WARD). Their main objective was to assess the clinical characteristics of patients with DM enrolled by type of admission, and the resource consumption and corresponding costs were estimated as secondary objectives.…”
Section: Introductionmentioning
confidence: 99%