“…This might be surprising at first sight, since the control of physical systems has been considered for some time in different physical contexts, such as quantum mechanics [ 23 , 24 , 25 , 26 ] and statistical mechanics [ 27 , 28 , 29 , 30 , 31 , 32 ]. A paradigmatic case of control of a mesoscopic system is that of an optically trapped colloidal particle [ 27 , 28 , 31 , 33 , 34 , 35 , 36 , 37 , 38 , 39 ]. When the confining potential is harmonic, the time dependence of the stiffness of the trap can be externally controlled, and one aims at optimising the connection between two given equilibrium states, corresponding to different values of the stiffness of the trap—i.e., the colloidal particle is being confined or deconfined.…”